Results 71 to 80 of about 4,429,101 (170)

Properties of Nisin Z and Distribution of Its Gene, nisZ, in Lactococcus lactis [PDF]

, 1993
Two natural variants of the lantibiotic nisin that are produced by Lactococcus lactis are known. They have a similar structure but differ in a single amino acid residue at position 27: histidine in nisin A and asparagine in nisin Z.
Mulders, John W.M.,, Hugenholtz, Jeroen, Kuipers, Oscar P.,, Hugenholtz, Jeroen,, Kuipers, Oscar P.; id_orcid, Kuipers, Oscar P., Vos, Willem M. de, Mulders, John W.M., Siezen, Roland J., Vos, Willem M. de,, Siezen, Roland J.,   +10 more
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Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer

, 2017
Since BRCA mutations are only responsible for 10-20% of cases of breast cancer in patients with early-onset or a family history and since next-generation sequencing technology allows the simultaneous sequencing of a large number of target genes, testing ...
郭文宏;盧彥伸;林璟宏;倪衍玄;郭頌鑫;黃愛珠;黃俊升;林柏翰;陳沛隆;王明暘;林季宏, Lin, Po-Han;Kuo, Wen-Hung;Huang, Ai-Chu;Lu, Yen-Shen;Lin, Ching-Hung;Kuo, Sung-Hsin;Wang, Ming-Yang;Liu, Chun-Yu;Cheng, Fiona Tsui-Fen;Yeh, Ming-Hsin;Li, Huei-Ying;Yang, Yu-Hsuan;Hsu, Yu-Hua;Fan, Sheng-Chih;Li, Long-Yuan;Yu, Sung-Liang;Chang, King-Jen;Chen, Pei-Lung;Ni, Yen-Hsuan;Huang, Chiun-Sheng   +1 more
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Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles. [PDF]

, 2014
Burkholderia pseudomallei (Bp) is the causative agent of the infectious disease melioidosis. To investigate population diversity, recombination, and horizontal gene transfer in closely related Bp isolates, we performed whole-genome sequencing (WGS) on ...
Studholme, David J., Holden, Mathew TG, Ong, C, Beacham, I, Parkhill, J, Harting, J, Chen, Swaine L., Mehershahi, K, Holden, Matthew T. G., Nandi, T, T.G. Holden, Matthew, Didelot, X, Peak, I, Baybayan, Primo, Peak, Ian, Sim, B, Hoon, CH, Nandi, Tannistha, Boddey, J, Boddey, Justin, Boddey, Justin A., Holden, Matthew, J. Studholme, David, Baybayan, P, Michell, S, Essex-Lopresti, AE, Guo, Yan, Sim, Bernice, Didelot, Xavier, Titball, Richard W., Chen, SL, Smither, Sophie, Smiters, Sophie, Beacham, Ifor, Holden, Matthew TG, Smither, S, How, LC, Nelson, Michelle, Ong, Catherine, Tan, P, Wang, S, Aw, LT, Nelson, M, Mitchell, Stephen, Michell, Stephen, Aw, Lay Tin, E. Essex-Lopresti, Angela, Chen, Swaine, Chen, Swaine L, Titball, Richard, Mehrashahi, Kurosh, Hoon, Chua Hui, Boddey, Justin A, Sarkar-Tyson, M, Parkhill, Julian, Mehershahi, Kurosh, Guo, Y, Tan, Patrick, How, Lee Chee, W. Titball, Richard, Sarkar-Tyson, Mitali, Wang, Susana, Essex-Lopresti, Angela, Studholme, David J, Harting, John   +64 more
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Serological and genetic analysis of a Bel subtype caused by a novel 29insG mutation: a case report

Zhongguo shuxue zazhi
Objective To investigate the serological characteristics and molecular mechanism of a case of Bel subtype. Methods Serological method was used to analyze the ABO blood group of the patient, absorption and elution test was used to detect the weak antigen ...
ZHOU Renlong, ZHANG Cuiyun, HUANG Guoqing   +2 more
doaj   +1 more source

Geoseq: a tool for dissecting deep-sequencing datasets [PDF]

, 2010
Gurtowski J, Cancio A, Shah H, et al. Geoseq: a tool for dissecting deep-sequencing datasets. BMC Bioinformatics. 2010;11(1): 506.Background Datasets generated on deep-sequencing platforms have been deposited in various public repositories such as the ...
Gurtowski, James, Sachidanandam, Ravi, Robert Homann, Shah Hardik, Chaya Levovitz, Ravi Sachidanandam, Hardik Shah, James Gurtowski, Cancio, Anthony, Levovitz Chaya, George Ajish, Cancio Anthony, Homann, Robert, Anthony Cancio, Shah, Hardik, Homann Robert, Levovitz, Chaya, Sachidanandam Ravi, Ajish George, George, Ajish, Gurtowski James   +20 more
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Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations. [PDF]

, 2011
Elevated plasma levels of lipoprotein-associated phospholipase A(2) (Lp-PLA2) activity have been shown to be associated with increased risk of coronary heart disease and an inhibitor of this enzyme is under development for the treatment of that condition.
Bacanu, S.A., E S Manas, Kong, X., Aponte, J., Manas, ES, S-A Bacanu, Cardon, L., Song, K, Nelson, MR, K Song, J Aponte, X Kong, Whittaker, JC, M R Nelson, Manas, E.S., Yuan, X., D M Waterworth, Whittaker, J.C., Kong, X, Cardon, L, Waterworth, DM, Yuan, X, L Cardon, Mooser, V.E., X Yuan, Song, K., Aponte, J, Bacanu, S-A, Nelson, M.R., Mooser, VE, J C Whittaker, Waterworth, D.M., V E Mooser   +32 more
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A case of special blood type with discrepancy between ABO genotype and serological results

Zhongguo shuxue zazhi
[Objective] To analyze the cause of discrepancy between ABO genotype B102/O01 and serological results in one case by PCR-SSP, to clarify the serological characteristics of this special blood group, and to explore relevant blood transfusion strategies ...
JIA Wenting, ZHANG Wei, CUI Limin
doaj   +1 more source

Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution

Medicines, 2017
Esophageal cancer (EC) is the eighth most common cancer and is the sixth leading cause of death worldwide. The incidence of histologic subtypes of EC, esophageal adenocarcinoma (EAC) and esophageal squamous carcinoma (ESCC), display considerable ...
Ugo Testa, Germana Castelli, Elvira Pelosi   +2 more
doaj   +1 more source

MediPlEx - a tool to combine in silico and experimental gene expression profiles of the model legume Medicago truncatula. [PDF]

, 2010
Henckel K, Küster H, Stutz L, Goesmann A. MediPlEx - a tool to combine in silico and experimental gene expression profiles of the model legume Medicago truncatula. BMC Research Notes.
Henckel, Kolja, Stutz Leonhard J, Henckel Kolja, Küster, Helge, Stutz, Leonhard, Küster Helge, Helge Küster, Kolja Henckel, Leonhard J Stutz, Goesmann, Alexander ; https://orcid.org/, Goesmann Alexander, Alexander Goesmann   +11 more
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Functional analysis of MEIS2 splice site variant c.438 + 1G>T in a congenital heart patient

Frontiers in Genetics
AimsMEIS2 (NCBI:4212; OMIM:601740) is associated with cleft palate, atrial septal defect, and varying degrees of intellectual disability. The aim of this study is to investigate the value of minigene splicing assay in the diagnosis of congenital heart ...
Chenyu Xu, Junjuan Li, Xinghui Ma, Wenqi Li, Bo Jiang, Hua Bai, Fuhong Wu, Chunlian Liu, Jiwei Gu   +8 more
doaj   +1 more source