Results 81 to 90 of about 4,429,101 (170)

Meta-Learning for Predictive Modeling of Antimicrobial Resistance in Dynamic Healthcare Environments

IEEE Access
Antimicrobial drug resistance is a growing global health concern characterized by microbes developing mutations to survive antimicrobial drugs. Although mutation among organisms is a natural evolutionary process, it can be enhanced by human activity ...
Matsiko Ian Sezi, Kasozi Mark Carlos, Lusiba Mark Collins, Bizimaana Gad William, Josephine Nabukenya, Irene Arinaitwe, Agnes Rwashana Semwanga, Ggaliwango Marvin   +7 more
doaj   +1 more source

X-linked hyper IgM syndrome with a novel CD40-ligand gene mutation suffered from infection of Talaromyces marneffei

Frontiers in Immunology
BackgroundX-linked Hyper-IgM Syndrome (X-HIGM) is a primary immunodeficiency caused by pathogenic variants in CD40L. Loss of functional CD40 ligand interferes with T-cell–dependent B-cell responses and immunoglobulin class-switch recombination, resulting
Juan Gu, Aiyan Ren, Aiyan Ren, Jing Kong, Meiying Huang, Meiying Huang, Huijuan Jin, Chengxin Sun, Chengxin Sun, Chengxin Sun, Shiji Xiao, Shiji Xiao, Shiji Xiao, Enming Zhang, Zuochen Du, Zuochen Du   +15 more
doaj   +1 more source

Virtual Environment for Next Generation Sequencing Analysis [PDF]

, 2012
Next Generation Sequencing technology, on the one hand, allows a more accurate analysis, and, on the other hand, increases the amount of data to process.
Provenzano, R., Provenzano R., Terzo, Olivier, Mossucca, L., Acquaviva, Andrea, Mossucca L, Abate, Francesco   +6 more
core  

Clinical value of genetic analysis in prenatal diagnosis of short femur

Molecular Genetics & Genomic Medicine, 2019
Background Fetal femur length (FL) is an important biometric index in prenatal screening. The etiology of short femur is diverse, with some pathogenic causes leading to adverse outcomes.
Jialiu Liu, Linhuan Huang, Zhiming He, Shaobin Lin, Ye Wang, Yanmin Luo   +5 more
doaj   +1 more source

The low recombining pericentromeric region of barley restricts gene diversity and evolution but not gene expression [PDF]

, 2014
The low-recombining pericentromeric region of the barley genome contains roughly a quarter of the genes of the species, embedded in low recombining DNA that is rich in repeats and repressive chromatin signatures.
Dhillon, Taniya, Milne, Iain, Baker, Katie, Colas, Isabelle, Bayer, Micha, Russell, Joanne, Marshall, David, Waugh, Robbie, Dreißig, Steven, Flavell, Andrew J., Ramsay, Luke, Steffenson, Brian, Stephen, Gordon, Dressig, Steven, Hedley, Pete E., Waugh, Robbie; id_orcid, Cook, Nicola, Morris, Jenny   +17 more
core   +1 more source

Analysis of ABO allelic enhancement phenomenon in 20 cases with ABO*AW.37 allele

Zhongguo shuxue zazhi
Objective To investigate the serological and molecular characteristics of twenty blood samples carrying ABO*AW.37 allele and to analyze ABO allelic enhancement. Methods The ABO phenotype of the twenty samples was determined by serological methods and the
Xian HUANG, Shuangyu LI, Tongtong LI, Lina WU, Jinhui XIE, Lei MA, Jinghui Chong, Shiping AN   +7 more
doaj   +1 more source

General lack of global dosage compensation in ZZ/ZW systems? Broadening the perspective with RNA-seq [PDF]

, 2011
Background Species with heteromorphic sex chromosomes face the challenge of large-scale imbalance in gene dose. Microarray-based studies in several independent male heterogametic XX/XY systems suggest that dosage compensation mechanisms are in place to ...
Bryk, Jaroslaw,, Bryk, Jarek, Wolf, Jochen B. W.,, Wolf, Jochen BW, Bryk Jarosław, Wolf, Jochen B. W., Jochen BW Wolf, Bryk, J., Bryk, Jarosłav, Wolf, J., Jarosław Bryk, Wolf Jochen BW   +11 more
core   +2 more sources

Factors influencing the spatial distributions of river microbial communities at the watershed scale: a case study involving the Wuding River Basin

Frontiers in Microbiology
Microbial communities regulate water quality and biogeochemical cycling in rivers, but their responses to geomorphological factors remain unclear. Water samples were collected in August 2024 (summer wet season) from the Wuding River, and metagenomic ...
Nan Xue, Nan Xue, Nan Xue, Manhong Xia, Manhong Xia, Manhong Xia, Bo Hu, Xinru Gong, Zhoufeng Wang, Zhoufeng Wang, Zhoufeng Wang, Xiaohong Zhao, Xiaohong Zhao   +12 more
doaj   +1 more source

Fluoroquinolone and Second-Line Injectable Resistance Among Rifampicin- and Isoniazid-Resistant Mycobacterium tuberculosis Clinical Isolates: A Molecular Study from a High-Burden Setting

Microorganisms
Drug-resistant tuberculosis (DR-TB) threatens global TB control. We investigated the prevalence and molecular characteristics of second-line drug resistance among rifampicin (RIF)- and/or isoniazid (INH)-resistant Mycobacterium tuberculosis complex (MTBC)
Rosângela Siqueira Oliveira, Angela Pires Brandao, Fabiane Maria de Almeida Ferreira, Sonia Maria da Costa, Vera Lucia Maria Silva, Lucilaine Ferrazoli, Erica Chimara, Juliana Maira Watanabe Pinhata   +7 more
doaj   +1 more source

Blood group changes in acute myeloid leukemia and their relationship with therapeutic effect

Zhongguo shuxue zazhi
Objective To explore the blood group changes of two acute myeloid leukemia patients with suspected O type, and their relationship with the therapeutic effect.
Qianqian SONG, Shuang YANG, Qianmeng HAO, Yulin ZHANG   +3 more
doaj   +1 more source