Results 191 to 200 of about 631,661 (355)

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Identification and Validation of Pyroptosis-Associated Gene Signature in Primary Sjögren's Syndrome. [PDF]

Mediators Inflamm
Dai Y, Chen H, Zhou M, Wu C, Gao F, Wang Y, Yan Q, Li Z.   +7 more
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Development of an ADME gene signature for prognostic and therapeutic stratification in gastric cancer. [PDF]

Discov Oncol
Wang D, Wang X, Chen L, Wang H, Meng X, Miao Z, Zhao Y.   +6 more
europepmc   +1 more source

Molecular Signatures from Gene Expression Data

, 2004
Ramón Díaz‐Uriarte
openalex   +2 more sources

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival [PDF]

, 2005
Howard Y. Chang, Dimitry S.A. Nuyten, Julie B. Sneddon, Trevor Hastie, Robert Tibshirani, Thérese Sørlie, Hongyue Dai, Yudong D. He, Laura J. van’t Veer, Harry Bartelink, Matt van de Rijn, Patrick O. Brown, Marc J. van de Vijver   +12 more
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Gene expression signatures for colorectal cancer microsatellite status and HNPCC [PDF]

, 2005
Mogens Kruhøffer, Jens Ledet Jensen, Päivi Laiho, Lars Dyrskjøt, Reijo Salovaara, Diego Arango, Karin Birkenkamp‐Demtröder, Flemming Brandt Sørensen, Lise-Lotte Christensen, Line Buhl, Jukka‐Pekka Mecklin, Heikki Järvinen, Thomas Thykjær, Friedrik P. Wikman, F Bech-Knudsen, Martti Juhola, Nina N. Nupponen, Søren Laurberg, Claus L. Andersen, Lauri A. Aaltonen, Torben F. Ørntoft   +20 more
openalex   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

BA9 Transcriptomics in Huntington's Disease 80-Gene Signature and MIR219A2-Linked Targets. [PDF]

Int J Mol Sci
Öztan G, İşsever H, Şahin L.
europepmc   +1 more source