Results 171 to 180 of about 3,125,604 (306)

A Cross-Region Meta-Analysis and Machine Learning Identifies a 37-Gene Signature Associated with Alzheimer's Disease. [PDF]

Biomedicines
Shah KC, Littlestone E, Ahmmad MR, Wang C, Xu Y, Zhang X.   +5 more
europepmc   +1 more source

Graphical and Digital signature Combination for fulfilling the cultural gap

, 2005
This proposal develops the concept of combining a handwritten signature, digital signature, and a smart card into an overall Public Key Infrastructure (PKI). The purpose of this proposed solution is to fulfill the cultural gap between traditional digital
Between Traditional Signature, Nazar Elfadil   +1 more
core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Kynurenine metabolism-related gene signature for prognostic stratification in hepatocellular carcinoma. [PDF]

Transl Cancer Res
Liu Y, Zhong C, Cai M, Lin X, Luo L.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

An Integrative Methylation-Metabolism Gene Signature Defines Prognosis and Immunosuppressive Microenvironment in Prostate Cancer. [PDF]

Chem Biol Drug Des
Zhang C, Liu L, Wu K.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

A Mitochondrial-Related Gene Signature for Diagnosis and Immune Microenvironment Modulation in Lung Cancer and Venous Thromboembolism. [PDF]

World J Oncol
Zhang XL, Gao AL, Liu ZJ.
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Mitochondria related gene signature serves as prognosis prediction and risk stratification of cholangiocarcinoma. [PDF]

Transl Cancer Res
Li S, Xiang W, Wei W, Zhang H, Xie Q, Yin B, Lin H, Xu S.   +7 more
europepmc   +1 more source