Results 191 to 200 of about 2,093,614 (359)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

P1386: USE OF A FOAMY-VIRUS VECTOR SYSTEM TO PRODUCE AN ‘OFF-THE-SHELF’ FCΓ-CR-T CELL PRODUCT FOR THE TREATMENT OF HEMATOLOGICAL AND SOLID TUMOR MALIGNANCIES

HemaSphere, 2023
Ioanna Lazana, Emmanouil Simantirakis, Euaggelos Kourous, Panayiota Fotopoulou, George Vassilopoulos   +4 more
doaj   +1 more source

Malignancy and gene therapy in hemophilia. [PDF]

Res Pract Thromb Haemost
Kaczmarek R.
europepmc   +1 more source

629 Assessing efficacy of airway gene therapy in neonatal rats

, 2022
A. McCarron, P. Cmielewski, D. Parsons, M. Donnelley   +3 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Gene Therapy-Related Malignancy and the Risk of Cancer Exceptionalism. [PDF]

J Clin Oncol
Benedetti DJ, Marron JM, Kodish E.
europepmc   +1 more source

Supplementary Data from Deconvolving Clinically Relevant Cellular Immune Cross-talk from Bulk Gene Expression Using CODEFACS and LIRICS Stratifies Patients with Melanoma to Anti–PD-1 Therapy

, 2023
Kun Wang, Sushant Patkar, Joo Sang Lee, E. Michael Gertz, Welles Robinson, Fiorella Schischlik, David R. Crawford, Alejandro A. Schäffer, Eytan Ruppin   +8 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Advances in Gene Therapy for Inherited Haemoglobinopathies. [PDF]

Hematol Rep
Gaspar AB, Gaspar HB.
europepmc   +1 more source

Recent Advances in Gene Therapy for Hemophilia

Xiaojuan Pang, Jian Fu, Zhongqi Zhou, Nannan Tang, Cia‐Hin Lau, Yingfei Wen, Ping Chen, Jing Zhao, Hongman Xue   +8 more
openalex   +1 more source