Results 231 to 240 of about 12,497,887 (407)

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Principles of gene therapy of the inner ear. [PDF]

Curr Opin Otolaryngol Head Neck Surg
Lin JS, Shibata SB.
europepmc   +1 more source

Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes.

, 1993
Richard J. Cristiano, Lawrence C. Smith, Savio L.C. Woo   +2 more
openalex   +1 more source

Barriers and Strategies of Cationic Liposomes for Cancer Gene Therapy

Molecular Therapy: Methods & Clinical Development, 2020
Chunyan Liu, Ligang Zhang, Wenhui Zhu, Raoqing Guo, Huamin Sun, Xi Chen, Ning Deng   +6 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Reality bites: allocating gene therapy for hemoglobinopathies. [PDF]

Blood Adv
Tubman VN, Fasipe TA.
europepmc   +1 more source

A Potential Approach for Gene Therapy Targeting Hepatoma Using a Liver-Specific Promoter on a Retroviral Vector.

, 1991
Shigeki Kuriyama, Masahide Yoshikawa, Shigeaki Ishizaka, Tadasu Tsujii, Kazuhiro Ikenaka, Tetsushi Kagawa, Noriyuki Morita, Katsuhiko Mikoshiba   +7 more
openalex   +1 more source

Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy [PDF]

, 1999
David E. Smith, Jeffrey A. Roberts, F H Gage, Mark H. Tuszynski   +3 more
openalex   +1 more source

Gene therapy [PDF]

Nature, 2018
openaire   +2 more sources

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source