Results 321 to 330 of about 12,313,232 (386)

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Emerging Strategies of Cell and Gene Therapy Targeting Tumor Immune Microenvironment. [PDF]

Clin Cancer Res
Wang R, Duan X, Li J, Zhang C, Shen L.
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Regulatory Elements for Gene Therapy of Epilepsy. [PDF]

Cells
Chesnokova E, Bal N, Alhalabi G, Balaban P.   +3 more
europepmc   +1 more source

Submission to the Committee on the Ethics of Gene Therapy [PDF]

, 1990
Joint Ethico-Medical Committee of the Catholic Union of Great Britain and the Guild of Catholic Doctors
core   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Editorial on Special Issue "Plasmid DNA for Gene Therapy and DNA Vaccine Applications". [PDF]

Pharmaceutics
Kamenšek U.
europepmc   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Protocol for minicircle production for gene therapy without subsequent cleanup steps. [PDF]

STAR Protoc
Do J, Verma G, Maurice Y, Abdumanobova M, Deng Z, Kalin TV, Kalinichenko VV.   +6 more
europepmc   +1 more source