Results 101 to 110 of about 560,494 (342)

Modeling, Simulation and Application of Bacterial Transduction in Genetic Algorithms [PDF]

, 2009
At present, all methods in Evolutionary Computation are bioinspired in the fundamental principles of neo-Darwinism as well as on a vertical gene transfer. Thus, on a mechanism in which an organism receives genetic material from its ancestor.
Carlos Perales-Gravan, Javier de Vicente Buendia, Rafael Lahoz-Beltra   +2 more
core   +2 more sources

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes

Infection and Drug Resistance, 2014
Jennifer R HuddlestonBiology Department, Abilene Christian University, Abilene, TX, USAAbstract: Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic resistance among pathogens.
Huddleston JR
doaj  

Chromosome architecture constrains horizontal gene transfer in bacteria.

PLoS Genetics, 2018
Despite significant frequencies of lateral gene transfer between species, higher taxonomic groups of bacteria show ecological and phenotypic cohesion. This suggests that barriers prevent panmictic dissemination of genes via lateral gene transfer. We have
Heather L Hendrickson, Dominique Barbeau, Robin Ceschin, Jeffrey G Lawrence   +3 more
doaj   +1 more source

Effective use of a horizontally-transferred pathway for dichloromethane catabolism requires post–transfer refinement [PDF]

, 2015
When microbes acquire new abilities through horizontal gene transfer, the genes and pathways must function under conditions with which they did not coevolve.
Bringel, Françoise, Camargo Neves, Aline A, Marx, Christopher J, Michener, Joshua K, Vuilleumier, Stéphane   +4 more
core   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes. [PDF]

PLoS Genetics, 2011
Gene duplication followed by neo- or sub-functionalization deeply impacts the evolution of protein families and is regarded as the main source of adaptive functional novelty in eukaryotes.
Todd J Treangen, Eduardo P C Rocha
doaj   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Ancient horizontal gene transfer and the last common ancestors [PDF]

, 2015
Background The genomic history of prokaryotic organismal lineages is marked by extensive horizontal gene transfer (HGT) between groups of organisms at all taxonomic levels. These HGT events have played an essential role in the origin and distribution of
A Barzel, A Burt, A Hua-Van, A Sauerwald, A Stoltzfus, AM Barbaglia, B Boussau, B Reisinger, C Darwin, Cheryl P Andam, CP Andam, CP Andam, CR Woese, CR Woese, D Darriba, D Williams, DA Benson, DH Rothman, EGJ Danchin, EV Koonin, EV Koonin, EV Koonin, G Borrel, G Borrel, G Eriani, G Srinivasan, GJ Szöllosi, GM Nagel, GP Fournier, GP Fournier, GP Fournier, Gregory P Fournier, H Grosjean, J Peretó, J Thomas, JA Krzycki, JA Krzycki, JAG Ranea, JL Siefert, JM Kavran, Johann Peter Gogarten, JP Gogarten, K Swithers, K Vetsigian, L Olendzenski, L Ribas de Pouplana, L Ribas de Pouplana, L Sinzelle, LS Frost, M Ibba, M Khomyakova, M Syvanen, M Wu, MH Mazauric, MV Omelchenko, N Lartillot, N Nameki, O Penn, O Zhaxybayeva, P Kück, P Kück, P O’Donoghue, P O’Donoghue, P Schimmel, R Dawkins, R Jain, RC Edgar, S Bilokapic, S Gould, S Guindon, S Herring, S Herring, S Morris, S Osawa, SQ Le, T Tuller, TJ Treangen, VV Kapitonov, WM Fitch, Y Diaz-Lazcoz, Y Zhang, YI Wolf, Z-P Fang   +82 more
core   +2 more sources

Detecting Highways of Horizontal Gene Transfer [PDF]

Journal of Computational Biology, 2011
In a horizontal gene transfer (HGT) event, a gene is transferred between two species that do not have an ancestor-descendant relationship. Typically, no more than a few genes are horizontally transferred between any two species. However, several studies identified pairs of species between which many different genes were horizontally transferred. Such a
Bansal, Mukul S., Banay, Guy, Gogarten, J. Peter, Shamir, Ron   +3 more
openaire   +3 more sources