Results 121 to 130 of about 560,494 (342)
Biology's next revolution [PDF]
, 2007 The interpretation of recent environmental genomics data exposes the far-reaching influence of horizontal gene transfer, and is changing our basic concepts of organism, species and evolution itself.Comment: Slightly expanded version of invited essay ...
Goldenfeld, Nigel, Woese, Carl
core +3 more sources
Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer
Nature Microbiology, 2020 CRISPR–Cas adaptive immune systems protect bacteria and archaea against their invading genetic parasites, including bacteriophages/viruses and plasmids.
C. Mahendra +5 more
semanticscholar +1 more source
Synthetic Fatty Acids Prevent Plasmid-Mediated Horizontal Gene Transfer
mBio, 2015 Bacterial conjugation constitutes a major horizontal gene transfer mechanism for the dissemination of antibiotic resistance genes among human pathogens.
María Getino +7 more
doaj +1 more source
Impacts of florfenicol on the microbiota landscape and resistome as revealed by metagenomic analysis. [PDF]
, 2019 BACKGROUND:Drug-resistant fish pathogens can cause significant economic loss to fish farmers. Since 2012, florfenicol has become an approved drug for treating both septicemia and columnaris diseases in freshwater fish.
Liao, Chao +3 more
core
Scientific Reports, 2019 Horizontal gene transfer (HGT) is widespread in the evolution of prokaryotes, especially those associated with the human body. Here, we implemented large-scale gene-species phylogenetic tree reconstructions and reconciliations to identify putative HGT ...
Hyeonsoo Jeong +4 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi +7 more
wiley +1 more source
Current and Promising Approaches to Identify Horizontal Gene Transfer Events in Metagenomes
Genome Biology and Evolution, 2019 High-throughput shotgun metagenomics sequencing has enabled the profiling of myriad natural communities. These data are commonly used to identify gene families and pathways that were potentially gained or lost in an environment and which may be involved ...
G. Douglas, M. Langille
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu +10 more
wiley +1 more source
Exosome-mediated horizontal gene transfer occurs in double-strand break repair during genome editing
Communications Biology, 2019 The CRISPR-Cas9 system has been successfully applied in many organisms as a powerful genome-editing tool. Undoubtedly, it will soon be applied to human genome editing, including gene therapy.
R. Ono +5 more
semanticscholar +1 more source
Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
Advanced Healthcare Materials, EarlyView.A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source