Results 61 to 70 of about 309,008 (294)

Horizontal gene transfer in bacteria: an ecological and evolutionary perspective

open access: yesActa Agriculturae Slovenica, 2000
In recent years, molecular genetics and genome analysis provided extensive evidence that gene loss and acquisition are likely to be the primary mechanisms by which bacteria genetically adapt to novel or changed environments and by which bacterial ...
Matjaž PETERKA   +2 more
doaj   +1 more source

Horizontal gene transfer in human pathogens. [PDF]

open access: yes, 2015
This is the accepted version of the original publication available at http://informahealthcare.com/doi/abs/10.3109/1040841X.2013.804031.Horizontal gene transfer has a tremendous impact on the genome plasticity, adaptation and evolution of bacteria ...
Juhas, Mario
core  

Bacterial sex in dental plaque [PDF]

open access: yes, 2013
Genes are transferred between bacteria in dental plaque by transduction, conjugation, and transformation. Membrane vesicles can also provide a mechanism for horizontal gene transfer.
Bing-Yan Wang   +11 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Topological data analysis captures horizontal gene transfer in antimicrobial resistance gene families among clinically relevant bacteria

open access: yesFrontiers in Microbiology
Antibiotic resistance, projected to cause 10 million deaths annually by 2050, remains a critical health threat. Hospitals drive multidrug resistance via horizontal gene transfer.
Shaday Guerrero-Flores   +6 more
doaj   +1 more source

Phase Diagrams of Quasispecies Theory with Recombination and Horizontal Gene Transfer

open access: yes, 2006
We consider how transfer of genetic information between individuals influences the phase diagram and mean fitness of both the Eigen and the parallel, or Crow-Kimura, models of evolution.
J. Maynard   +4 more
core   +1 more source

Experimental design and statistical rigor in phylogenomics of horizontal and endosymbiotic gene transfer [PDF]

open access: yes, 2011
A growing number of phylogenomic investigations from diverse eukaryotes are examining conflicts among gene trees as evidence of horizontal gene transfer.
John W Stiller
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Gene silencing and large-scale domain structure of the E. coli genome

open access: yes, 2012
The H-NS chromosome-organizing protein in E. coli can stabilize genomic DNA loops, and form oligomeric structures connected to repression of gene expression.
Lagomarsino, Marco Cosentino   +2 more
core   +2 more sources

Loss of very-long O-antigen chains optimizes capsule-mediated immune evasion by Salmonella enterica serovar Typhi. [PDF]

open access: yes, 2013
UnlabelledExpression of capsular polysaccharides is a variable trait often associated with more-virulent forms of a bacterial species. For example, typhoid fever is caused by the capsulated Salmonella enterica serovar Typhi, while nontyphoidal Salmonella
Bäumler, Andreas J   +5 more
core   +1 more source

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