Results 81 to 90 of about 287,974 (300)

Genomic islands: tools of bacterial horizontal gene transfer and evolution [PDF]

, 2017
Bacterial genomes evolve through mutations, rearrangements or horizontal gene transfer. Besides the core genes encoding essential metabolic functions, bacterial genomes also harbour a number of accessory genes acquired by horizontal gene transfer that ...
Crook, Derrick W., Gaillard, Muriel, Harding, Rosalind M., Hood, Derek W., Juhas, Mario, van der Meer, Jan Roelof   +5 more
core  

A probabilistic model for gene content evolution with duplication, loss, and horizontal transfer

, 2005
We introduce a Markov model for the evolution of a gene family along a phylogeny. The model includes parameters for the rates of horizontal gene transfer, gene duplication, and gene loss, in addition to branch lengths in the phylogeny. The likelihood for
A.B. Simonson, B. Boussau, B. Snel, B. Snel, B.E. Dutilh, B.G. Mirkin, C. Pál, C.G. Kurland, D.H. Huson, E. Belda, E.A. Herniou, E.D. Green, E.J. Deeds, E.L.L. Sonnhammer, E.V. Koonin, F. Delsuc, F. Tekaia, G.D.P. Clarke, G.P. Karev, G.P. Karev, G.P. Karev, I.K. Jordan, J. Lin, J.A. Lake, J.O. Korbel, J.P. Gogarten, J.T. Herbeck, K.H. Wolfe, M. Csűrös, M. Pellegrini, M.G. Montague, M.W. Hahn, R.L. Tatusov, S. Karlin, S. Yang, S.T. Fitz-Gibbon, T. Pupko, V. Kunin, V. Kunin, W. Feller, W.J. Reed, X. Gu, Y. Boucher, Y.I. Wolf   +43 more
core   +2 more sources

Massive Horizontal Gene Transfer in Bdelloid Rotifers [PDF]

, 2008
Horizontal gene transfer in metazoans has been documented in only a few species and is usually associated with endosymbiosis or parasitism. By contrast, in bdelloid rotifers we found many genes that appear to have originated in bacteria, fungi, and ...
Arkhipova, Irina, Gladyshev, Evgeniy, Meselson, Matthew   +2 more
core   +1 more source

Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes. [PDF]

PLoS Genetics, 2011
Gene duplication followed by neo- or sub-functionalization deeply impacts the evolution of protein families and is regarded as the main source of adaptive functional novelty in eukaryotes.
Todd J Treangen, Eduardo P C Rocha
doaj   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes

Infection and Drug Resistance, 2014
Jennifer R HuddlestonBiology Department, Abilene Christian University, Abilene, TX, USAAbstract: Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic resistance among pathogens.
Huddleston JR
doaj  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Ancestral genome estimation reveals the history of ecological diversification in Agrobacterium [PDF]

, 2017
Horizontal gene transfer (HGT) is considered as a major source of innovation in bacteria, and as such is expected to drive adaptation to new ecological niches.
Barbe, V, Bigot, T, Calteau, A, Chapulliot, D, Daubin, V, Dubost, A, Guéguen, L, Lassalle, F, Mornico, D, Muller, D, Nesme, X, Penel, S, Planel, R, Vallenet, D, Vial, L   +14 more
core   +3 more sources

Does habitat variability really promote metabolic network modularity? [PDF]

PLoS ONE, 2013
The hypothesis that variability in natural habitats promotes modular organization is widely accepted for cellular networks. However, results of some data analyses and theoretical studies have begun to cast doubt on the impact of habitat variability on ...
Kazuhiro Takemoto
doaj   +1 more source

Horizontal gene transfer and bacterial diversity [PDF]

Journal of Biosciences, 2002
Bacterial genomes are extremely dynamic and mosaic in nature. A substantial amount of genetic information is inserted into or deleted from such genomes through the process of horizontal transfer. Through the introduction of novel physiological traits from distantly related organisms, horizontal gene transfer often causes drastic changes in the ...
Chitra Dutta, Archana Pan
openaire   +2 more sources