Results 191 to 200 of about 1,625,963 (355)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Genomic Evolution and Patterns of Horizontal Gene Transfer in Coccomorpha Species. [PDF]

Ecol Evol
Huang YX, Lv JM, Ding CY, Zheng XY, Liu XJ, Chen XN, Yu SH, Meng YF, Hu HY, Wang X.   +9 more
europepmc   +1 more source

The significance of controlled conditions in lentiviral vector titration and in the use of multiplicity of infection (MOI) for predicting gene transfer events [PDF]

, 2004
Bing Zhang, Pat Metharom, Howard Jullie, K.A.O. Ellem, G. J. Cleghorn, Malcolm West, Wei Ming   +6 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

In Silico Prediction of Horizontal Gene Transfer Events in Lactobacillus bulgaricus and Streptococcus thermophilus Reveals Protocooperation in Yogurt Manufacturing

, 2009
Mengjin Liu, Roland J. Siezen, Arjen Nauta   +2 more
openalex   +1 more source

Gene transfer to hepatocellular carcinoma: Transduction efficacy and transgene expression kinetics by using retroviral and lentiviral vectors [PDF]

, 2000
René Gerolami, Rathviro Uch, François Jordier, S. Chapel, Claude Bagnis, Christian Bréchot, P Mannoni   +6 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Gold Nanoparticles-Enhanced Gene Transfer Driven by MHz-Frequency Nanosecond Pulsed Electric Fields. [PDF]

Biomolecules
Malyško-Ptašinskė V, Radzevičiūtė-Valčiukė E, Szewczyk A, Lekešytė B, Malakauskaitė P, Mickevičiūtė-Zinkuvienė E, Želvys A, German N, Kulbacka J, Novickij V.   +9 more
europepmc   +1 more source

Gene Transfer of Extracellular Superoxide Dismutase Failed to Prevent Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage [PDF]

, 2004
Mitsuo Yamaguchi, Changman Zhou, Donald D. Heistad, Yoshimasa Watanabe, John H. Zhang   +4 more
openalex   +1 more source

Gene transfer [PDF]

Bone Marrow Transplantation, 2000
openaire   +1 more source