Results 211 to 220 of about 10,802,441 (400)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Horizontal gene transfer of molecular weapons can reshape bacterial competition. [PDF]

PLoS Biol
Granato ET, Palmer JD, Kirk C, Sharp C, Shillcock G, Foster KR.   +5 more
europepmc   +1 more source

Degradation of monochlorinated aromatics following transfer of genes encoding chlorocatechol catabolism [PDF]

, 1982
Walter Reineke, Stephen W. Wessels, Miguel A. Rubio, Javier Latorre, Uwe Schwien, Eberhardt Schmidt, Michael Schlömann, Hans‐Joachim Knackmuss   +7 more
openalex   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Benchmarking pangenome dynamics and horizontal gene transfer in <i>Mycobacterium marinum</i> evolution. [PDF]

Front Microbiol
Shahed K, Islam SI, Sangsawad P, Jung WK, Permpoonpattana P, Linh NV.   +5 more
europepmc   +1 more source

Total synthesis of a tyrosine suppressor transfer RNA gene. XIII. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence -1 to -29 in the promoter region.

, 1979
R Belagaje, Eugene L. Brown, Michael J. Gait, H. G. Khorana, Kjeld Norris   +4 more
openalex   +1 more source

Transfer RNA genes inDrosophilamitochondrial DNA: related 5' flanking sequences and comparisons to mammalian mitochondrial tRNA genes [PDF]

, 1983
Douglas O. Clary, Jill A. Wahleithner, David R. Wolstenholme   +2 more
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

The complete mitochondrial genome of Sinojackia microcarpa: evolutionary insights and gene transfer. [PDF]

BMC Genomics
Zhong T, Huang S, Liu R, Zhuo J, Lu H, Gan C, Fu J, Qian Q.   +7 more
europepmc   +1 more source

Gene Transfer in the Environment [PDF]

Environmental Science & Technology, 2001
openaire   +3 more sources