Results 121 to 130 of about 17,767 (219)

A MOSAIC of methods: Improving ortholog detection through integration of algorithmic diversity

, 2014
Ortholog detection (OD) is a critical step for comparative genomic analysis of protein-coding sequences. In this paper, we begin with a comprehensive comparison of four popular, methodologically diverse OD methods: MultiParanoid, Blat, Multiz, and OMA ...
Hernandez, Ryan D., Maher, M. Cyrus
core   +2 more sources

Appraisal of Gene Expression‐Based Classifiers for Neuropsychiatric Disorders: A Meta‐Regression

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 2, Page 93-104, March 2026.
ABSTRACT A substantial body of research examines the potential of gene‐expression‐based biomarkers for diagnosing and selecting treatments for neuropsychiatric disorders, yet no clear consensus has been reached regarding the influence of controllable factors such as study design and model selection on the performance of gene‐expression‐based ...
Ali Razavi, Brittany Arensman, Eric J. Barnett, Leo A. Lee, Stephen V. Faraone, Stephen J. Glatt, Jonathan L. Hess   +6 more
wiley   +1 more source

Phylogeography and Contact Zones of the Common Grass Snake in Poland (Squamata: Natricidae: Natrix natrix)

Zoologica Scripta, Volume 55, Issue 2, Page 209-219, March 2026.
ABSTRACT Until now, the genetic identity of common grass snakes (Natrix natrix) in Poland remained poorly understood. This study presents the first comprehensive phylogeographic analysis for Poland using mitochondrial DNA sequences (cyt b and ND4 + tRNAs) and 13 nuclear microsatellite loci.
Andrea Criado‐Flórez, Daniel Jablonski, Bartosz Borczyk, Stanisław Bury, Krzysztof Kolenda, Katarzyna Kurek, Sławomir Mitrus, Bartłomiej Najbar, Maciej Pabijan, Beata Prusak, Tomasz Skawiński, Bartłomiej Zając, Uwe Fritz   +12 more
wiley   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 256-269, February 2026.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips

Advanced Biology, Volume 10, Issue 2, February 2026.
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck, Jeroen Bugter, Gizem Yorukoglu, Mina Kazemzadeh Dastjerd, Thomas E. Winkler   +4 more
wiley   +1 more source

An approximate likelihood method reveals ancient gene flow between human, chimpanzee and gorilla

Peer Community Journal
Gene flow and incomplete lineage sorting are two distinct sources of phylogenetic conflict, i.e., gene trees that differ in topology from each other and from the species tree.
Galtier, Nicolas
doaj   +1 more source

Simulating the pathway from life history to phylogeny

New Phytologist, EarlyView.
Kieran N. Althaus, Andrew L. Hipp
wiley   +1 more source

Targeted blood proteome profiling using NULISAseq identifies a high‐performance biomarker panel for Aβ pathology quantification and staging

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION While current blood‐based biomarkers for Alzheimer's disease (AD) are effective for determining amyloid beta (Aβ) pathology positivity/negativity, they are insufficient for quantifying Aβ plaque deposition. METHODS We profiled 325 plasma proteins in a Hong Kong Chinese cohort using the Nucleic Acid Linked Immuno‑Sandwich Assay ...
Wenyue Zheng, Yuanbing Jiang, Hiu Yi Wong, Wan Wa Wong, Lily K. W. Cheng, Elaine Y. L. Cheng, Bonnie W. Y. Wong, Ronnie M. N. Lo, Siu Ki Leung, Fanny C. Ip, Jacqueline K. Y. Yuen, Yat Fung Shea, Wai Ming Wong, Chun Keung Shum, Hok Man Wai, Vincent C. T. Mok, Timothy C. Y. Kwok, Kin Y. Mok, Amanda Heslegrave, John Hardy, Henrik Zetterberg, Amy K. Y. Fu, Nancy Y. Ip   +22 more
wiley   +1 more source

Demographic Models and Behavioral Assessments Uncover Distinct Species Histories in the Pseudocryptic Nudibranch Genus Hermissenda

Ecology and Evolution, Volume 16, Issue 2, February 2026.
We reconstructed the speciation history of the recently split pseudocryptic nudibranch genus Hermissenda, finding divergence times in the Pleistocene (1.29–0.55 mya). Demographic modeling and behavioral experiments show no gene flow and assortative mating between sympatric species H. crassicornis (s.s.) and H.
Miranda T. Dennis, Austin L. Ka’ala Estores‐Pacheco, Keilan Williams, Russell C. Wyeth, Ángel Valdés, Arne Ø. Mooers, Michael W. Hart   +6 more
wiley   +1 more source

Evolution and Climate Adaptation in Eurasian Gyrfalcon Populations

Ecology and Evolution, Volume 16, Issue 2, February 2026.
This reports the influence of past, current and future Arctic climate change to the evolution of Eurasian gyrfalcons (Falco rusticolus), and reveals that its current evolutionary potential is insufficient to cope with the ongoing Arctic warming. ABSTRACT Climate change is considered a key driver for shaping ecological and evolutionary processes of ...
Xin Liu, Li Hu, Zhenzhen Lin, Shengkai Pan, Siying Huang, Vasiliy Sokolov, Aleksandr Sokolov, Ivan Fufachev, Sergey Ganusevich, Andrew Dixon, Xiangjiang Zhan   +10 more
wiley   +1 more source