The Origin of a New Sex Chromosome by Introgression between Two Stickleback Fishes. [PDF]
Introgression is increasingly recognized as a source of genetic diversity that fuels adaptation. Its role in the evolution of sex chromosomes, however, is not well known. Here, we confirm the hypothesis that the Y chromosome in the ninespine stickleback,
Abbott +78 more
core +1 more source
Forcing external constraints on tree inference using ASTRAL
Background To account for genome-wide discordance among gene trees, several widely-used methods seek to find a species tree with the minimum distance to input gene trees.
Maryam Rabiee, Siavash Mirarab
doaj +1 more source
Data concatenation, Bayesian concordance and coalescent-based analyses of the species tree for the rapid radiation of Triturus newts. [PDF]
The phylogenetic relationships for rapid species radiations are difficult to disentangle. Here we study one such case, namely the genus Triturus, which is composed of the marbled and crested newts.
Ben Wielstra +4 more
doaj +1 more source
Coalescent histories for lodgepole species trees
Coalescent histories are combinatorial structures that describe for a given gene tree and species tree the possible lists of branches of the species tree on which the gene tree coalescences take place. Properties of the number of coalescent histories for
Disanto, Filippo, Rosenberg, Noah A.
core +1 more source
Hybridization and extensive mitochondrial introgression among fire salamanders in peninsular Italy [PDF]
Discordance between mitochondrial and nuclear patterns of population genetic structure is providing key insights into the eco-evolutionary dynamics between and within species, and their assessment is highly relevant to biodiversity monitoring practices ...
Arduino, Paola +4 more
core +2 more sources
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Dissecting discordance of mitochondrial and nuclear phylogenetic trees in insects
The mitochondrial and nuclear genomes present distinct inheritance and genomic structural characteristics. Although both genomes have been widely used for phylogenetic tree reconstruction, topological discordances between trees inferred from ...
Xianfeng Mi +3 more
doaj +1 more source
Inferring Species Trees from Incongruent Multi-Copy Gene Trees Using the Robinson-Foulds Distance [PDF]
We present a new method for inferring species trees from multi-copy gene trees. Our method is based on a generalization of the Robinson-Foulds (RF) distance to multi-labeled trees (mul-trees), i.e., gene trees in which multiple leaves can have the same ...
Burleigh, J. Gordon +2 more
core +2 more sources
Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang +12 more
wiley +1 more source
Transcriptome analysis provides new insights into cold adaptation of corsac fox (Vulpes Corsac)
Vulpesare widely distributed throughout the world and have undergone drastic physiological and phenotypic changes in response to their environment. However, little is known about the underlying genetic causes of these traits, especially Vulpes corsac. In
Xiufeng Yang +8 more
doaj +1 more source

