Results 171 to 180 of about 30,515,316 (293)

Use of point-of-care resources for management of paediatric asthma: frequency, types and temporal trends in early-career general practitioners. [PDF]

Fam Med Community Health
Reid N, Fisher K, Ralston A, Tapley A, Holliday EG, Mitchell B, Charlton I, Chen K, Dizon J, Moad D, Fielding A, Davey A, van Driel M, Clarke L, Spurling G, Magin P.   +15 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Scottish GP walk-in centres: access at the expense of continuity? [PDF]

Br J Gen Pract
Hughes LD, McCartney M, Sullivan F.
europepmc   +1 more source

Sensation - general. [PDF]

Psychological Bulletin, 1911
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Efficacy and safety of antibiotic regimens for <i>Helicobacter pylori</i> eradication: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Liao Y, Liu H, Zhou Y, Wang Z.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Uptake and Costs of the 60-Day Dispensing Policy for Antihypertensive Medicines in Australia: A Mixed Methods Study. [PDF]

Med J Aust
Wang T, Nguyen HL, Tan I, Picone DS, Atkins E, Gnanenthiran SR, Falster MO, Pearson SA, Rodgers A, Schutte AE.   +9 more
europepmc   +1 more source

Against Intellectual Monopoly [PDF]

David K Levine, Michele Boldrin
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source