Results 171 to 180 of about 520,423 (307)

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

AgBioDatabase Finder: an online tool to help researchers find and submit agricultural genomic, genetic, and breeding data. [PDF]

MicroPubl Biol
Cabugos L, Buble K, Daenzer J, Jung S, Main D, Marrano A, Molik D, Raciti D, Wright A, Yook K, Reiser L.   +10 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Intoxications and knowledge about toxicological information centers in undergraduate students in the state of Jalisco, Mexico. [PDF]

Aten Primaria
Rojas-Prado E, Hernández-Pérez MA, Vázquez-Alvarez AO, Huerta-Olvera SG.   +3 more
europepmc   +1 more source

Leaks in the pipeline: separating demographic inertia from ongoing gender differences in academia

Proceedings of the Royal Society B: Biological Sciences, 2012
Allison K. Shaw, D. Stanton
semanticscholar   +1 more source

MDP25‐VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis

Advanced Science, EarlyView.
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou, Pengfei Lu, Xuan Cui, Liangfeng Luo, Qing Pan, Jiejie Li   +5 more
wiley   +1 more source

The stunt of stunted silk: A novel pollination control mechanism in maize. [PDF]

Plant Physiol
Aboobuckerصديق أبوبكر SI, Talekar SC, Frei UK, Yang B, Lübberstedt T.   +4 more
europepmc   +1 more source

Renaissance Learning And Poetry Contests In Biological And Agricultural Engineering

, 2004
A. Christy
semanticscholar   +1 more source

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

Identification of Transcription Factors of <i>GmHPL</i> Involved in Modulating Pathogen Stresses in Soybean. [PDF]

Plants (Basel)
Wang Y, Lyu W, Li S, Fu M, Yu X, Zhao Z, Hu S, Xu H.   +7 more
europepmc   +1 more source