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Mechanisms of General Anesthesia [PDF]
Environmental Health Perspectives, 1990 Although general anesthetics are often said to be nonspecific agents, it is likely that they act at a much more restricted set of target sites than commonly believed. The traditional view has been that the primary targets are lipid portions of nerve membranes, but recent evidence shows that the effects on lipid bilayers of clinically relevant levels of
William R. Lieb, Nicholas P. Franks
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Dental treatment under general anesthesia for patients with severe disabilities
Journal of dental anesthesia and pain medicine, 2021 Patients with disabilities have difficulties tolerating in-office dental treatment due to limitations relating to cooperation and/or physical problems. Therefore, they often require general anesthesia or sedation to facilitate safe treatment.
Junglim Choi, Re-mee Doh
semanticscholar +1 more source
The association between gut microbiota and postoperative delirium in patients
Translational Psychiatry, 2023 Postoperative delirium is a common postoperative complication in older patients, and its pathogenesis and biomarkers remain largely undetermined. The gut microbiota has been shown to regulate brain function, and therefore, it is vital to explore the ...
Yiying Zhang +9 more
doaj +1 more source
Neural Substrates for the Regulation of Sleep and General Anesthesia
Current Neuropharmacology, 2021 General anesthesia has been successfully used in clinics for over 170 years, but its mechanisms of effect remain unclear. Behaviorally, general anesthesia is similar to sleep as it produces a reversible transition between wakefulness and the state of ...
Qianzi Yang +3 more
semanticscholar +1 more source
Propofol Induction Reduces the Capacity for Neural Information Integration: Implications for the Mechanism of Consciousness and General Anesthesia [PDF]
, 2008 The cognitive unbinding paradigm suggests that the synthesis of cognitive information is attenuated by general anesthesia. Here, we investigated the functional organization of brain activities in the conscious and anesthetized states, based on ...
Byung-Moon Choi +4 more
core +2 more sources
Cognitive dysfunction following desflurane versus sevoflurane general anesthesia in elderly patients: a randomized controlled trial. [PDF]
, 2014 UnlabelledAs life expectancy increases, more patients ≥65 years undergo general anesthesia. Anesthetic agents may contribute to postoperative cognitive dysfunction, and incidence may differ with anesthetic agents or intraoperative anesthesia depth ...
Allard, Martin +7 more
core +1 more source
General anesthesia does not have persistent effects on attention in rodents [PDF]
, 2019 Background: Studies in animals have shown that general anesthesia can cause persistent spatial memory impairment, but the influence of anesthetics on other cognitive functions is unclear.
Amanda G. Nelson +8 more
core +2 more sources
Sleep and general anesthesia [PDF]
Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2010 The mechanisms through which general anesthetics cause reversible loss of consciousness are characterized poorly. In this review, we examine the evidence that anesthetic-induced loss of consciousness may be caused by actions on the neuronal pathways that produce natural sleep.It is clear that many general anesthetics produce effects in the brain ...
Anna Y. Zecharia, Nicholas P. Franks
openaire +2 more sources
JA Clinical Reports, 2023 Background We report the anesthetic management of inguinal hernia repair for an infant with subglottic stenosis. A previously scheduled operation had been cancelled due to unexpected airway trouble during the induction.
Yumi Doi, Satoshi Ekuni
doaj +1 more source
Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases [PDF]
, 2014 Prevention and treatment of intraoperative hypoxemia in horses is difficult and both efficacy and safety of therapeutic maneuvers have to be taken into account.
AE Wagner +24 more
core +4 more sources