Results 21 to 30 of about 7,819,121 (415)

Long-term Survival after Combined Epidural–General Anesthesia or General Anesthesia Alone: Follow-up of a Randomized Trial

Anesthesiology, 2021
Background: Experimental and observational research suggests that combined epidural–general anesthesia may improve long-term survival after cancer surgery by reducing anesthetic and opioid consumption and by blunting surgery-related inflammation.
Yaoan Du, Ya-wei Li, Bin-Jiang Zhao, Xiang-yang Guo, Yi Feng, M. Zuo, C. Fu, Weijun Zhou, H. Li, Ya-Fei Liu, T. Cheng, D. Mu, Y. Zeng, Peng Liu, Yan Li, H. An, Sai-nan Zhu, Xueying Li, Hui-juan Li, Yang-feng Wu, Dong-Xin Wang, D. Sessler   +21 more
semanticscholar   +1 more source

Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit

Anesthesia and Analgesia, 2021
BACKGROUND: Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic drugs ...
C. Ing, R. Landau, David DeStephano, Caleb H. Miles, B. V. von Ungern-Sternberg, Guohua Li, A. Whitehouse   +6 more
semanticscholar   +1 more source

Noninvasive respiratory support for COVID-19 patients: when, for whom, and how?

Journal of Intensive Care, 2022
The significant mortality rate and prolonged ventilator days associated with invasive mechanical ventilation (IMV) in patients with severe COVID-19 have incited a debate surrounding the use of noninvasive respiratory support (NIRS) (i.e., HFNC, CPAP, NIV)
Zachary P. Sullivan, Luca Zazzeron, Lorenzo Berra, Dean R. Hess, Edward A. Bittner, Marvin G. Chang   +5 more
doaj   +1 more source

Neural Substrates for the Regulation of Sleep and General Anesthesia

Current Neuropharmacology, 2021
General anesthesia has been successfully used in clinics for over 170 years, but its mechanisms of effect remain unclear. Behaviorally, general anesthesia is similar to sleep as it produces a reversible transition between wakefulness and the state of ...
Qianzi Yang, Fang Zhou, Ao Li, Hailong Dong   +3 more
semanticscholar   +1 more source

Mechanisms of General Anesthesia [PDF]

Environmental Health Perspectives, 1990
Although general anesthetics are often said to be nonspecific agents, it is likely that they act at a much more restricted set of target sites than commonly believed. The traditional view has been that the primary targets are lipid portions of nerve membranes, but recent evidence shows that the effects on lipid bilayers of clinically relevant levels of
William R. Lieb, Nicholas P. Franks
openaire   +3 more sources

The association between gut microbiota and postoperative delirium in patients

Translational Psychiatry, 2023
Postoperative delirium is a common postoperative complication in older patients, and its pathogenesis and biomarkers remain largely undetermined. The gut microbiota has been shown to regulate brain function, and therefore, it is vital to explore the ...
Yiying Zhang, Kathryn Baldyga, Yuanlin Dong, Wenyu Song, Mirella Villanueva, Hao Deng, Ariel Mueller, Timothy T. Houle, Edward R. Marcantonio, Zhongcong Xie   +9 more
doaj   +1 more source

Propofol Induction Reduces the Capacity for Neural Information Integration: Implications for the Mechanism of Consciousness and General Anesthesia [PDF]

, 2008
The cognitive unbinding paradigm suggests that the synthesis of cognitive information is attenuated by general anesthesia. Here, we investigated the functional organization of brain activities in the conscious and anesthetized states, based on ...
Byung-Moon Choi, George A. Mashour, Gyu-Jeong Noh, Seunghwan Kim, UnCheol Lee   +4 more
core   +2 more sources

Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]

, 2015
Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana, Cannata, Riccardo, Collini, Saul, Malagola, Romualdo, Migliorini, Raffaele, Servidio, Annalisa   +5 more
core   +1 more source

Sleep and general anesthesia [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2010
The mechanisms through which general anesthetics cause reversible loss of consciousness are characterized poorly. In this review, we examine the evidence that anesthetic-induced loss of consciousness may be caused by actions on the neuronal pathways that produce natural sleep.It is clear that many general anesthetics produce effects in the brain ...
Anna Y. Zecharia, Nicholas P. Franks
openaire   +2 more sources

Comparison of Anesthesia for Dental/Oral Surgery by Office-based Dentist Anesthesiologists versus Operating Room-based Physician Anesthesiologists [PDF]

, 2017
Few studies have examined the practice characteristics of dentist anesthesiologists and compared them to other anesthesia providers. Using outcomes from the National Anesthesia Clinical Outcomes Registry and the Society for Ambulatory Anesthesia Clinical
Gabriel, Rodney A., Jones, James E., Saxen, Mark A., Urman, Richard D., Yepes, Juan F.   +4 more
core   +1 more source