Results 41 to 50 of about 617,895 (318)

Dexmedetomidine inhibits the lipopolysaccharide‐stimulated inflammatory response in microglia through the pathway involving TLR4 and NF‐κB

Kaohsiung Journal of Medical Sciences, 2019
To investigate the effects of dexmedetomidine (DEX) on lipopolysaccharide (LPS)‐induced neuroinflammation in BV2 microglia. BV2 microglial cells were treated with various concentrations of DEX (0, 1, 10, and 100 ng/mL) for 1 hour, and then incubated in ...
Xue‐Yue Zhou, Jing Liu, Zhi‐Peng Xu, Qiang Fu, Pei‐Qi Wang, Hong Zhang   +5 more
doaj   +1 more source

Combined general -spinal anesthesia versus combined general - epidural anesthesia for Laparoscopic Hysterectomy [PDF]

Minia Journal of Medical Research
Background: General anesthesia (GA) is the preferred anesthetic technique for laparoscopic hysterectomy(LH). However, laparoscopic surgery is accompanied with marked stress response, Adding regional techniques, to GA was used to overcome these ...
Wegdan Ali, Ibrahim Youssef, Ahmed Ismail, Ali Abdelwahab   +3 more
doaj   +1 more source

A lung rescue team improves survival in obesity with acute respiratory distress syndrome

Critical Care, 2020
Background Limited data exist regarding ventilation in patients with class III obesity [body mass index (BMI) > 40 kg/m2] and acute respiratory distress syndrome (ARDS). The aim of the present study was to determine whether an individualized titration of
Gaetano Florio, Matteo Ferrari, Edward A. Bittner, Roberta De Santis Santiago, Massimiliano Pirrone, Jacopo Fumagalli, Maddalena Teggia Droghi, Cristina Mietto, Riccardo Pinciroli, Sheri Berg, Aranya Bagchi, Kenneth Shelton, Alexander Kuo, Yvonne Lai, Abraham Sonny, Peggy Lai, Kathryn Hibbert, Jean Kwo, Richard M. Pino, Jeanine Wiener-Kronish, Marcelo B. P. Amato, Pankaj Arora, Robert M. Kacmarek, Lorenzo Berra, For the investigators of the lung rescue team   +24 more
doaj   +1 more source

Higher occurrence of nausea and vomiting after total hip arthroplasty using general versus spinal anesthesia: an observational study. [PDF]

, 2016
BACKGROUND: Under the assumption that postoperative nausea and vomiting (PONV) may occur after total hip arthroplasty (THA) regardless of the anesthetic technique used, it is not clear whether general (GA) or spinal (SA) anesthesia has higher causal ...
A Borgeat, A Borgeat, A Harsten, A Kauste, A Kovac, AD Macdowell, B Fischer, Bernard Burnand, C Black, CC Apfel, CJ Lin, D Rusch, DE Ho, EA Stuart, F Clergue, FJ Singelyn, H Wulf, HS Smith, IUMSP, J Fortier, J Hahn, JB Cooper, JL Schafer, Julien Sansonnens, K Beyer, K Imai, KV Sanborn, LL Leape, M Coory, M McKee, M Stadler, MA Hernán, MR Brinker, P Diemunsch, P Taffe, Patrick Taffé, PC Austin, PC Austin, PR Rosenbaum, RH Dehejia, RL Johnson, S Fasting, S Greenland, TJ Gan, TJ Gan, TM DiIorio, V Pittet   +46 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice

Journal of Neuroinflammation, 2019
Background It is widely accepted that mitochondria have a direct impact on neuronal function and survival. Oxidative stress caused by mitochondrial abnormalities play an important role in the pathophysiology of lipopolysaccharide (LPS)-induced memory ...
Weixing Zhao, Zhipeng Xu, Jiangbei Cao, Qiang Fu, Yishuang Wu, Xiaoying Zhang, Yue Long, Xuan Zhang, Yitian Yang, Yunfeng Li, Weidong Mi   +10 more
doaj   +1 more source

Preoperative anemia and total hospitalization time are the independent factors of preoperative deep venous thromboembolism in Chinese elderly undergoing hip surgery

BMC Anesthesiology, 2020
Background This study was designed to explore the prevalence and risk factors of preoperative deep venous thromboembolism (DVT) in Chinese elderly with hip fracture.
Long Feng, Longhe Xu, Weixiu Yuan, Zhipeng Xu, Zeguo Feng, Hong Zhang   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Lung (extracorporeal CO2 removal) and renal (continuous renal replacement therapy) support: the role of ultraprotective strategy in Covid 19 and non-Covid 19 ARDS. A case-control study

Journal of Anesthesia, Analgesia and Critical Care
Background Preliminary studies suggest that moderate ARDS and acute renal failure might benefit from extracorporeal CO2 removal (ECCO2R) coupled with CRRT. However, evidence is limited and potential for this coupled treatment may need to be explored. The
Daniela Pasero, Laura Pistidda, Davide Piredda, Corrado Liperi, Andrea Cossu, Raffaella Esposito, Angela Muroni, Cristiano Mereu, Carlino Rum, Gian Pietro Branca, Franco Mulas, Mariangela Puci, Giovanni Sotgiu, Pierpaolo Terragni   +13 more
doaj   +1 more source

Myocardial Infarction After General Anesthesia [PDF]

, 1972
Few statistics are available about the incidence of primary or recurrent myocardial infarction after anesthesia. Mortality rates and their relation to age and sex, and to type and duration of anesthesia in existing reports, are based on a relatively ...
Giuliani, Emilio R., Moffitt, Emerson A., Tarhan, Sait, Taylor, William F.   +3 more
core   +2 more sources