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Peripheral neuropathy is a dose-limiting side effect of chemotherapy with paclitaxel. Paclitaxel-induced peripheral neuropathy (PIPN) is typically characterized by a predominantly sensory neuropathy presenting with allodynia, hyperalgesia and spontaneous
Mariko Ezaka +11 more
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Mechanisms of General Anesthesia [PDF]
Although general anesthetics are often said to be nonspecific agents, it is likely that they act at a much more restricted set of target sites than commonly believed. The traditional view has been that the primary targets are lipid portions of nerve membranes, but recent evidence shows that the effects on lipid bilayers of clinically relevant levels of
N P, Franks, W R, Lieb
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New patents on topical anesthetics. [PDF]
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano +6 more
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Sleep and general anesthesia [PDF]
The mechanisms through which general anesthetics cause reversible loss of consciousness are characterized poorly. In this review, we examine the evidence that anesthetic-induced loss of consciousness may be caused by actions on the neuronal pathways that produce natural sleep.It is clear that many general anesthetics produce effects in the brain ...
Nicholas P, Franks, Anna Y, Zecharia
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Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR +8 more
core +1 more source
Comparison of Anesthesia for Dental/Oral Surgery by Office-based Dentist Anesthesiologists versus Operating Room-based Physician Anesthesiologists [PDF]
Few studies have examined the practice characteristics of dentist anesthesiologists and compared them to other anesthesia providers. Using outcomes from the National Anesthesia Clinical Outcomes Registry and the Society for Ambulatory Anesthesia Clinical
Gabriel, Rodney A. +4 more
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Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study [PDF]
Objective: To evaluate the effect of anesthesia type on the risk of in-hospital mortality among adults undergoing hip fracture surgery in the United States. Design: Retrospective cohort study.
Bateman, Brian T +4 more
core +1 more source
The anesthetic sevoflurane induces tau trafficking from neurons to microglia
Using their previously developed nanobeam-sensor technology to detect tau protein in the blood, Yuanlin Dong et al. find that the anaesthetic sevoflurane induces trafficking of tau from neurons to microglia in mice.
Yuanlin Dong +8 more
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A novel multivariate STeady-state index during general ANesthesia (STAN) [PDF]
The assessment of the adequacy of general anesthesia for surgery, namely the nociception/anti-nociception balance, has received wide attention from the scientific community. Monitoring systems based on the frontal EEG/EMG, or autonomic state reactions (e.
A Albertin +34 more
core +1 more source
The discordance between increased physiological demand during pregnancy and congenital cardiac pathology of a parturient is a perilous threat to the maternal-fetal well-being.
Huili Lim +4 more
doaj +1 more source

