Results 51 to 60 of about 6,840,055 (366)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte

Journal of Neuroinflammation, 2020
Background Ischemic stroke is the second leading cause of death globally. The narrow time window for administering effective thrombolytic therapy motivates the search for alternative prevention strategies.
Min Liu, Zhipeng Xu, Long Wang, Lixia Zhang, Yi Liu, Jiangbei Cao, Qiang Fu, Yanhong Liu, Hao Li, Jingsheng Lou, Wugang Hou, Weidong Mi, Yulong Ma   +12 more
doaj   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Lung (extracorporeal CO2 removal) and renal (continuous renal replacement therapy) support: the role of ultraprotective strategy in Covid 19 and non-Covid 19 ARDS. A case-control study

Journal of Anesthesia, Analgesia and Critical Care
Background Preliminary studies suggest that moderate ARDS and acute renal failure might benefit from extracorporeal CO2 removal (ECCO2R) coupled with CRRT. However, evidence is limited and potential for this coupled treatment may need to be explored. The
Daniela Pasero, Laura Pistidda, Davide Piredda, Corrado Liperi, Andrea Cossu, Raffaella Esposito, Angela Muroni, Cristiano Mereu, Carlino Rum, Gian Pietro Branca, Franco Mulas, Mariangela Puci, Giovanni Sotgiu, Pierpaolo Terragni   +13 more
doaj   +1 more source

Surgical pulmonary embolectomy on VA-ECMO

Respiratory Medicine Case Reports, 2021
Surgical pulmonary embolectomy is a procedure that is often used to rescue patients with massive pulmonary embolism (PE) and circulatory collapse that have failed or may not be ideal candidates for other systemic and endovascular treatment modalities ...
Rachel Steinhorn, Adam A. Dalia, Edward A. Bittner, Marvin G. Chang   +3 more
doaj   +1 more source

Association of Higher Levels of High‐Sensitivity C‐Reactive Protein With Future Development of Psoriatic Arthritis in Psoriasis: A Prospective Cohort Study

Arthritis Care &Research, EarlyView.
Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder, Xianwei Li, Vinod Chandran, Cheryl F. Rosen, Richard J. Cook, Dafna D. Gladman   +5 more
wiley   +1 more source

Screening for Social Determinants of Health in Patients With Systemic Lupus Erythematosus: A Point‐of‐Care Feasibility Study

Arthritis Care &Research, EarlyView.
Objective Social determinants of health (SDoH) can impact outcomes but are not routinely screened for in US outpatient rheumatology clinics. This study determined the feasibility of routine point‐of‐care SDoH screening among patients with systemic lupus erythematosus (SLE) and associated barriers and facilitators at the physician, care team, and ...
S. Sam Lim, Vijay R. Nadipelli, Michelle Bruno, Daphne Lew, Bernard Rubin, Charmayne M. Dunlop‐Thomas, Kelsey Hulcher, Kristi R. Mitchell, Lydia Demetriou, Jeff Berko, Jason Bao, Alfred H. J. Kim   +11 more
wiley   +1 more source

Possible iodophor-induced systemic iodine toxicity during transurethral seminal vesiculoscopy: a case report and literature review

BMC Urology
Rationale Iodophor, a disinfectant composed of iodine complexed with a surfactant, is extensively employed for preoperative skin preparation, burn wound management, and mucosal disinfection.
Meng Zhang, Nan Zhao, Huanhuan Zhang, Jianli Li   +3 more
doaj   +1 more source

Effect of nitric oxide on postoperative acute kidney injury in patients who underwent cardiopulmonary bypass: a systematic review and meta-analysis with trial sequential analysis

Annals of Intensive Care, 2019
Background The effect of nitric oxide (NO) on renal function is controversial in critical illness. We performed a systematic meta-analysis and trial sequential analysis to determine the effect of NO gas on renal function and other clinical outcomes in ...
Jie Hu, Stefano Spina, Francesco Zadek, Nikolay O. Kamenshchikov, Edward A. Bittner, Juan Pedemonte, Lorenzo Berra   +6 more
doaj   +1 more source

Improving the accuracy of revised cardiac risk index with HbA1C: Hemoglobin ratio (HH ratio) – A retrospective cohort study

Frontiers in Medicine, 2023
BackgroundThe current Lee’s Revised cardiac risk index (RCRI) was created in 1999. Validation studies have found RCRI to be only moderately discriminant.
Yuhe Ke, Nicholas Brian Shannon, Hairil Rizal Abdullah   +2 more
doaj   +1 more source