, 2016 Anesthetic agents are neurotropic drugs able to induce dramatic alterations in the thalamo-cortical system, promoting a drastic reduction in awareness and level of consciousness.
Padovani, Eduardo C.
core
K2P channels and their protein partners. [PDF]
, 2005 A decade since their discovery, the K2P channels are recognized as pathways dedicated to regulated background leakage of potassium ions that serve to control neuronal excitability. The recent identification of protein partners that directly interact with
Goldstein, Steve AN +2 more
core +1 more source
Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment
Arthritis Care &Research, EarlyView.Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histologic features and treatment response.
Andrea Fava +48 more
wiley +1 more source
Neurophysiologic Effects of General Anesthetics [PDF]
, 1973 Burton S. Rosner, Donald L. Clark
openalex +1 more source
The changes of pharmacokinetic behavior of the medical substances as a consequence of the „in vivo” interaction with general anesthetics [PDF]
Medicamentul Veterinar, 2007 General anesthetics are substances which produce a reversible state of unconsciousness and insensibility. Inaddition to these principal effects, anesthetics modify almost always, the other functions of the organism.
Năstasă V.,, Maria-Magdalena Nechifor
doaj
Effects of General Anesthetics on Excitatory and Inhibitory Synaptic Transmission in Area CA1 of the Rat Hippocamptls In Vitro [PDF]
, 1999 It is unclear whether general anesthetics induce enhancement of neural inhibition and/or attenuation of neural excitation.We studied the effects of pentobarbital (5xl0^mol/L), propofol (5x10^ mol/L), ketamine (10^ mol/L), halothane (1.5 vol%) and ...
Wakasugi Masahiro
core +1 more source
Impact of Positive Lifestyle Behaviors on Direct Health Care Cost Savings for Low Back Pain
Arthritis Care &Research, EarlyView.Objective This study aimed to investigate the relationship between a previously purpose‐developed lifestyle behavior scale and health care cost savings related to low back pain (LBP). Methods This longitudinal study used data from the Australian Twin Back (AUTBACK) study. LBP and lifestyle behavior measures were collected at baseline. Physical activity
Ye Tian +8 more
wiley +1 more source
Understanding the Molecular Mechanism of Anesthesia: Effect of General Anesthetics and Structurally Similar Non-Anesthetics on the Properties of Lipid Membranes. [PDF]
J Phys Chem B, 2023 Rózsa ZB +4 more
europepmc +1 more source
ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. [PDF]
, 2019 Background:Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous activation of β-arrestin (a signaling pathway associated with opioid-related AEs) and G ...
Beard, Timothy L +10 more
core
Arthritis Care &Research, EarlyView.Objective The objectives of this study were to evaluate the correlation and agreement between ultrasonography and computed tomography (CT) in measuring ascending aorta diameter in patients with giant cell arteritis (GCA) and to investigate the development of new ascending aortic aneurysms in patients with newly diagnosed GCA.
Anne C. Bull Haaversen +4 more
wiley +1 more source