Results 91 to 100 of about 11,347,707 (376)
Science, 2015 Telomeres are the protective end-complexes at the termini of eukaryotic chromosomes. Telomere attrition can lead to potentially maladaptive cellular changes, block cell division, and interfere with tissue replenishment.
E. Blackburn, E. Epel, Jue Lin
semanticscholar +1 more source
Nano-palladium is a cellular catalyst for in vivo chemistry
Nature Communications, 2017 Palladium (Pd) is a well-known catalyst in organic chemistry but its use in nanomedicine is limited. Here, the authors design a Pd nanoparticle that triggers the activation of an antitumour prodrugin vivo, which shows efficacy and improves toxicity ...
Miles A. Miller +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology
Pharmacological Reviews, 2017 The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel BoNTs are being discovered owing to next generation sequencing, but their biologic and pharmacological properties remain largely unknown.
M. Pirazzini +3 more
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Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Julian Huxley, general biology and the London Zoo, 1935–42
Notes and Records of the Royal Society, 2010 While Secretary of the Zoological Society of London (1935–42), Julian Huxley used that institution to undertake several types of reform related to his promotion of ‘general biology’.
J. Cain
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Nature Communications, 2018 Diagnostic tests need optimization to avoid invasive and costly repeated biopsies. Here the authors present an antibody-DNA barcoding approach where harvested single cells can be re-stained through custom oligonucleotide-fluorophore conjugates, enabling ...
Randy J. Giedt +6 more
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Developing a Web-Based Learning (E-Learning) in General Biology Subjects with Joomla Program
Biosfer, 2018 Web-based learning has been widely used as learning resources. Developing these learning resources is believed to provide beneficial for students. Therefore, this research was aimed to develop a web-based learning source for General Biology Course.
Muhamad Nurdin Matondang Seribulan +2 more
doaj +1 more source
arXiv, 2014 It is often stated that there are no laws in biology, where everything is contingent and could have been otherwise, being solely the result of historical accidents. Furthermore, the customary introduction of fundamental biological entities such as individual organisms, cells, genes, catalysts and motors remains largely descriptive; constructive ...
arxiv
Controlled vocabularies and semantics in systems biology [PDF]
, 2011 The use of computational modeling to describe and analyze biological systems is at the heart of systems biology. Model structures, simulation descriptions and numerical results can be encoded in structured formats, but there is an increasing need to ...
Courtot, Mélanie, Hucka, Michael
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