Results 121 to 130 of about 4,521,682 (346)
The maximum of a random walk reflected at a general barrier
We define the reflection of a random walk at a general barrier and derive, in case the increments are light tailed and have negative mean, a necessary and sufficient criterion for the global maximum of the reflected process to be finite a.s.
Hansen, Niels Richard
core +2 more sources
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren+16 more
wiley +1 more source
Qualitative analysis of differential equations [PDF]
Here I introduce basic methods of qualitative analysis of differential equations used in mathematical biology for people with minimal mathematical background.
arxiv
The General Biology Course and the Teaching of Elementary Botany and Zoology in American Colleges and Universities [PDF]
George Nichols
openalex +1 more source
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
A (possible) mathematical model to describe biological "context-dependence" : case study with protein structure [PDF]
Context-dependent nature of biological phenomena are well documented in every branch of biology. While there have been few previous attempts to (implicitly) model various facets of biological context-dependence, a formal and general mathematical construct to model the wide spectrum of context-dependence, eludes the students of biology. An objective and
arxiv
Generative Models for Synthetic Biology
Over the past several years, the fields of synthetic biology and machine learning have demonstrated marked advances in the scale of their capabilities and the success of their applications. The work presented in this thesis focuses on the translation of recent advances in machine learning toward new applications in synthetic biology.
openaire +3 more sources
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler+12 more
wiley +1 more source
Negative Energy: Why Interdisciplinary Physics Requires Multiple Ontologies
Much recent work in physics education research has focused on ontological metaphors for energy, particularly the substance ontology and its pedagogical affordances.
Dreyfus, Benjamin W.+5 more
core +1 more source