Results 51 to 60 of about 1,527,976 (335)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The Finite Element Sea Ice-Ocean Model (FESOM) v.1.4: formulation of an ocean general circulation model

, 2014
. The Finite Element Sea Ice-Ocean Model (FESOM) is the first global ocean general circulation model based on unstructured-mesh methods that has been developed for the purpose of climate research.
Qiang Wang, S. Danilov, D. Sidorenko, R. Timmermann, C. Wekerle, Xuezhu Wang, T. Jung, J. Schröter   +7 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Comparison of Artificial Neural Network (ANN) and SDSM Model to Downscaling of Temperature [PDF]

علوم و مهندسی آبیاری, 2017
In this study downscaling of temperature was down in Tajan Plain located in the province of Mazandaran. The result of atmospheric general circulation models was obtained with HadCM3 climate model under scenario A2. Since the output of atmospheric general
majid sheidaeian, mirkhalegh ziatabar ahmadi, ramin Fazl ola   +2 more
doaj   +1 more source

The effects of climate change on the risk of cold stress in autumn crop pattern ( Case study : Tropical and subtropical areas of Kerman province) [PDF]

مخاطرات محیط طبیعی, 2020
This research was carried out to evaluate the effect of climate change on changes in cold stress on potato plants in tropical regions of Kerman province. In this study, changes in the occurrence of cold stress in the observation data of three stations of
Fateme Bayatani, Gholam Abas Fallah Ghalhar, Mokhtar Karami, Javad Taei Semiromi   +3 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

GISS‐E2.1: Configurations and Climatology

Journal of Advances in Modeling Earth Systems, 2020
This paper describes the GISS‐E2.1 contribution to the Coupled Model Intercomparison Project, Phase 6 (CMIP6). This model version differs from the predecessor model (GISS‐E2) chiefly due to parameterization improvements to the atmospheric and ocean model
Maxwell Kelley, Gavin A. Schmidt, Larissa S. Nazarenko, Susanne E. Bauer, Reto Ruedy, Gary L. Russell, Andrew S. Ackerman, Igor Aleinov, Michael Bauer, Rainer Bleck, Vittorio Canuto, Grégory Cesana, Ye Cheng, Thomas L. Clune, Ben I. Cook, Carlos A. Cruz, Anthony D. Del Genio, Gregory S. Elsaesser, Greg Faluvegi, Nancy Y. Kiang, Daehyun Kim, Andrew A. Lacis, Anthony Leboissetier, Allegra N. LeGrande, Ken K. Lo, John Marshall, Elaine E. Matthews, Sonali McDermid, Keren Mezuman, Ron L. Miller, Lee T. Murray, Valdar Oinas, Clara Orbe, Carlos Pérez García‐Pando, Jan P. Perlwitz, Michael J. Puma, David Rind, Anastasia Romanou, Drew T. Shindell, Shan Sun, Nick Tausnev, Kostas Tsigaridis, George Tselioudis, Ensheng Weng, Jingbo Wu, Mao‐Sung Yao   +45 more
doaj   +1 more source

Seasonal variability in the Central Mediterranean Sea circulation [PDF]

Annales Geophysicae, 2003
A high resolution eddy-resolving primitive equation numerical model, based on the Princeton Ocean Model (POM), is used to study the seasonal variability of the general circulation in the Central Mediterranean Sea.
R. Sorgente, A. F. Drago, A. Ribotti
doaj   +1 more source

Evaluation of the Surface Representation of the Greenland Ice Sheet in a General Circulation Model

, 2014
Simulated surface conditions of the Goddard Earth Observing System model, version 5 (GEOS-5), atmospheric general circulation model (AGCM) are examined for the contemporary Greenland Ice Sheet (GrIS).
R. Cullather, S. Nowicki, Bin Zhao, M. Suárez   +3 more
semanticscholar   +1 more source