A nested Atlantic-Mediterranean Sea general circulation model for operational forecasting [PDF]
A new numerical general circulation ocean model for the Mediterranean Sea has been implemented nested within an Atlantic general circulation model within the framework of the Marine Environment and Security for the European Area project (MERSEA ...
P. Oddo +5 more
doaj
Coupling general ocean circulation models with the BFM marine ecosystem model
The coupling of numerical geophysical models of a sea with marine ecosystem models is considered. For the latter, BFM was chosen and coupled with three Russian models for three seas of different spatial scales: the White Sea (JASMINE), the Arctic Ocean ...
Ilya A. Chernov
doaj +1 more source
Coupling the PLANKTOM5.0 marine ecosystem model to the OCCAM 1º ocean general circulation model for investigation of the sensitivity of global biogeochemical cycles to variations in ecosystem complexity and physical environment [PDF]
The earliest marine ecosystem models consisted of a simple representation of the main features of marine ecosystems, including, typically, variables for phytoplankton, zooplankton, nutrient and detritus (NPZD models).
Anderson, T.R., Sinha, B.
core
Volcanic forcing improves Atmosphere-Ocean Coupled General Circulation Model scaling performance
Recent Atmosphere-Ocean Coupled General Circulation Model (AOGCM) simulations of the twentieth century climate, which account for anthropogenic and natural forcings, make it possible to study the origin of long-term temperature correlations found in the ...
A. Bunde +34 more
core +1 more source
The effects of latent heat release on the climate of an aquaplanet model [PDF]
As the atmosphere warms under climate change, it will hold more moisture. Latent heat released as water vapour condenses provides an important contribution to the atmospheric heat budget, affecting stability and providing complex feedbacks. Consequently,
Geen, Ruth
core +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
JIGSAW-GEO (1.0): locally orthogonal staggered unstructured grid generation for general circulation modelling on the sphere [PDF]
An algorithm for the generation of non-uniform, locally-orthogonal staggered unstructured spheroidal grids is described. This technique is designed to generate very high-quality staggered Voronoi/Delaunay meshes appropriate for general circulation ...
Engwirda, Darren
core +2 more sources
General circulation models of Hycean worlds
ABSTRACT Sub-Neptunes represent the current frontier of exoplanet atmospheric characterization. A proposed subset, Hycean planets, would have liquid water oceans and be potentially habitable, but there are many unanswered questions about their atmospheric dynamics and 3D climate states.
Edouard F L Barrier, Nikku Madhusudhan
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source

