Results 61 to 70 of about 400,675 (266)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Assessment of gene action and combining ability for fibre and yield contributing trais in interspecific and intraspecific hybrids of cotton

Czech Journal of Genetics and Plant Breeding, 2018
Combining ability analysis was performed in order to identify high-yielding genotypes and hybrids. Six lines were crossed with three testers using a line × tester mating design. General combining ability (GCA) of parents, specific combining ability (SCA)
Sana MUNIR, Muhammad Kamran QURESHI, Ahmad Naeem SHAHZAD, Hamid MANZOOR, Muhammad Ahmad SHAHZAD, Kashif ASLAM, Habib-Ur-Rehman ATHAR   +6 more
doaj   +1 more source

GENERAL AND SPECIFIC COMBINING ABILITY OF TROPICAL MAIZE GERMPLASM

Tropical and Subtropical Agroecosystems, 2008
Eight tropical maize populations were crossed in a diallel system. Parent and their 28 crosses were evaluated for grain yield in two plantations in 2006. The objective was to estimate the general combining ability (GCA) of the parental populations and the specific combining ability (SCA) of the crosses for grain yield. The populations were: 21, 22, 23,
Pedro Guillen de la Cruz, Efraín De La Cruz Lázaro, Guillermo Castañon Najera, Rodolfo Osorio Osorio, Nancy Patricia Brito Manzano, Alejandro Lozano del Río, Ulises López Noverola   +6 more
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Elucidating the genetic potential of hybrids derived from elite maize (Zea mays L.) inbreds for economic traits under North-Western Himalayan condition

Electronic Journal of Plant Breeding
This study was conducted to evaluate the combining ability of newly acquired maize inbred lines over the environments. Twenty-eight crosses developed by crossing eight elite inbreds in a half-diallel mating design were evaluated during kharif, 2019 for ...
Gaurav Sharma*, Uttam Chandel, Sawan Kumar, Satish Kumar Guleria and Nimit Kumar
doaj   +1 more source

Consequences of Truncation Selection Based on Combinations of Individual Performance and General Combining Ability [PDF]

Australian Journal of Biological Sciences, 1962
The objective of this study is to examine in detail the immediate and longterm oonsequenoes of nine oombinations of trunoation seleotion. These oombinations result from applying one of the following oonditions to eaoh sex: (i) no seleotion, (ii) individual seleotion, and (iii) general oombining ability seleotion.
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

RECURRENT SELECTION FOR GENERAL AND SPECIFIC COMBINING ABILITY IN MAIZE

IRAQI JOURNAL OF AGRICULTURAL SCIENCES
This study was aimed to identify efficiency  of recurrent  selection program to improve maize population. This program was applied to var. Buhooth 106 with var. 5012  Using RGCA  with the inbred Zm7 for the production of RSCA. The recurrent selection program was implemented for four consecutive seasons (2020 - 2021) at the Fields Station of the College
Zeyad A. Abdulhamed, Nihad.M. Abood, Abdulsamad. H. Noaman   +2 more
openaire   +2 more sources