Results 121 to 130 of about 3,454,963 (308)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Research in Science EducationAbstract Generative Artificial Intelligence (GenAI) holds promise as a tool to assist teachers in addressing specific instructional design and implementation tasks. This study explores how teachers in a master’s-level elementary science methods course used Large Language Model AI, as one type of GenAI, to design lessons fostering students ...
openaire +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
AbstractThe adoption of Generative Artificial Intelligence (GenAI) tools is drastically changing the way that researchers work. While debate on the quality of GenAI outputs continues, there is optimism that GenAI may help human experts to address the most significant environmental challenges facing society.
David Worden, Daniel Richards
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
How trade patterns and technology flows affect productivity growth [PDF]
Earlier studies of spillovers from international research and development (R&D) suggest how economies benefit from R&D conducted abroad. To the extent that countries importing new technologies do not pay in full for the increased variety in intermediate ...
Keller, Wolfgang
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How fundamental materials science will generate revolutionary breakthroughs in environmental monitoring technologies [PDF]
, 2014 Cloud-based computing infrastructure with enormous storage capability, coupled with new tools for remotely accessing, analysing and visualising data, is developing at an exponential rate in terms of the variety and scale of available information. The ‘sensor web’ is an area of particular interest, with many major industries increasingly looking at ...
openaire
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Vulnerability : a view from different disciplines [PDF]
Practitioners from different disciplines use different meanings and concepts of vulnerability, which, in turn, have led to diverse methods of measuring it.
Alwang, Jeffrey +2 more
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