Results 121 to 130 of about 44,272,182 (308)
, 2014 Higher education is one of the actors in the whole education system providing platform for access of people from different branches of science, different views and perceptions and creating possibilities for more environmentally friendly and sustainable ...
Dagiliūtė, Renata, Niaura, Andrius
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Presentation: Black Swans & the U.S. Future: Creating Sustainable & Resilient Societies [PDF]
, 2012 ‘Black Swans’ are infrequent and unpredictable events that can drive change in both human and natural systems. What qualities make societies resilient and sustainable in the face of environmental Black Swans?
Orr, David W. +1 more
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Abstract The adoption of Generative Artificial Intelligence (GenAI) tools is drastically changing the way that researchers work. While debate on the quality of GenAI outputs continues, there is optimism that GenAI may help human experts to address the most significant environmental challenges facing society.
David Worden, Daniel Richards
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ISEE Conference Abstracts, 2011 Background and Aims: The study explores which science-policy activities have been undertaken in the case studies of two EU consortium projects funded under the EU 6th Framework Programme: INTARESE ...
EM Kunseler, AB Knol
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Proceedings of Asian Symposium on Global Environmental Change, Tokyo, 1-2 December 1992
, 1993 At head of title: IGBP, global change."CGER-A008-'93"--Cover.Organized by Japan National Committee for the International Geosphere-Biosphere Programme, Science Council of Japan, Center for Global Environmental Research, National Institute for ...
Center for Global Environmental Research, National Institute for Environmental Studies, Environment Agency of Japan +1 more
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Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source