Results 71 to 80 of about 741,789 (265)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Citizen Science: Theory and Practice, 2016 New citizen science projects are emerging all the time as scientists, policy-makers, and non-governmental organisations see the value of conducting research in this way.
Sarah West, Rachel Pateman
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Communicating environmental science to the general public [PDF]
Integrated Environmental Assessment and Management, 2016 Thomas, Backhaus +1 more
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
School performance in science: adequacy of an evaluation system for students with learning disorders
Revista Brasileira de Ensino de Ciência e Tecnologia, 2019 The objective was to build and tailor a performance instrument large-scale science to Brazilian students with possible indicators of specific functional learning disorders.
Tiago Santos de Jesus +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Construindo pontes entre ciência e sociedade: divulgação científica sobre irradiação de alimentos
Brazilian Journal of Radiation Sciences, 2018 Food irradiation is a safe and effective preservation technique to eliminate insects and parasites and reduce disease-causing microorganisms. The process helps to inhibit sprouting and delay ripening, prolonging the shelf-life of fresh fruits and ...
Denise S. Levy +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Applications of Generative Large Language Models in Environmental Science: A Systematic Review
Advances in Environmental and Engineering ResearchEnvironmental science addresses critical global challenges, including climate change, biodiversity loss, and sustainability. These complex topics generate a vast amount of both structured and unstructured data, from remote sensing output to policy documents, guidelines, and scientific literature. Effectively processing and utilizing this information is
Mohammadi Raeissi-Hermans, M. +1 more
openaire +2 more sources