Results 81 to 90 of about 42,388 (275)

Theoretical Analysis of Fractional Viscoelastic Flow in Circular Pipes: General Solutions

open access: yesApplied Sciences, 2020
Fractional calculus is a relatively old yet emerging field of mathematics with the widest range of engineering and biomedical applications. Despite being an incredibly powerful tool, it, however, requires promotion in the engineering community.
Dmitry Gritsenko, Roberto Paoli
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Generalized fractional calculus with applications to the calculus of variations

open access: yesComputers & Mathematics with Applications, 2012
Submitted 22-Dec-2011; revised 26-Jan-2012; accepted 27-Jan-2012; for publication in Computers and Mathematics with ...
Odzijewicz, T.   +2 more
openaire   +4 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Inequalities for B $\mathbb{B}$-convex functions via generalized fractional integral

open access: yesJournal of Inequalities and Applications, 2019
Recently, fractional calculus has become a very popular and important area. Specially, fractional integral inequalities have been studied by different authors.
Ilknur Yesilce
doaj   +1 more source

Fractional isoperimetric Noether's theorem in the Riemann-Liouville sense

open access: yes, 2013
We prove Noether-type theorems for fractional isoperimetric variational problems with Riemann-Liouville derivatives. Both Lagrangian and Hamiltonian formulations are obtained. Illustrative examples, in the fractional context of the calculus of variations,
Almeida   +39 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Operational Calculus for the 1st-Level General Fractional Derivatives and Its Applications

open access: yesMathematics
The 1st-level General Fractional Derivatives (GFDs) combine in one definition the GFDs of the Riemann–Liouville type and the regularized GFDs (or the GFDs of the Caputo type) that have been recently introduced and actively studied in the fractional ...
Maryam Alkandari, Yuri Luchko
doaj   +1 more source

Fractional differential equations solved by using Mellin transform

open access: yes, 2014
In this paper, the solution of the multi-order differential equations, by using Mellin Transform, is proposed. It is shown that the problem related to the shift of the real part of the argument of the transformed function, arising when the Mellin ...
Butera, Salvatore, Di Paola, Mario
core   +1 more source

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