Results 91 to 100 of about 15,213 (267)
Abstract and Applied Analysis, 2013 The one-dimensional heat equations with the heat generation arising in fractal transient conduction associated with local fractional derivative operators are investigated.
Ai-Ming Yang +3 more
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
On a Generic Fractional Derivative Associated with the Riemann–Liouville Fractional Integral
AxiomsIn this paper, a generic fractional derivative is defined as a set of the linear operators left-inverse to the Riemann–Liouville fractional integral. Then, the theory of the left-invertible operators developed by Przeworska-Rolewicz is applied to deduce its properties.
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2017 In this work, we consider a class of fractional stochastic differential system with Hilfer fractional derivative and Poisson jumps in Hilbert space. We study the existence and uniqueness of mild solutions of such a class of fractional stochastic system ...
Fathalla A. Rihan +2 more
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
On the generalized fractional derivatives and their Caputo modification
The Journal of Nonlinear Sciences and Applications, 2017 Summary: In this manuscript, we define the generalized fractional derivative on \(AC^n_\gamma [a, b]\), the space of functions defined on \([a,b]\) such that \(\gamma^{n-1}f\in AC[a, b]\), where \(\gamma=x^{1-p}\frac{d}{dx}\). We present some of the properties of generalized fractional derivatives of these functions and then we define their Caputo ...
Jarad, F., Abdeljawad, T., Baleanu, D.
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FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
On generalized composite fractional q-derivative
Le Matematiche, 2015 In the present paper, we define a generalized composite fractional q-derivative D^{\alpha,\beta,\nu}_q and obtain some results for it. These results are image of power function under D^{\alpha,\beta,\nu}_q, composition of Riemann-Liouville type fractional q-integral I^\alpha_q with D^{\alpha,\beta,\nu}_q and q-Laplace transform of D^{\alpha,\beta,\nu}
Mridula Garg +2 more
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source