Results 101 to 110 of about 12,897,520 (259)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Technical note on a new definition of fractional derivative

open access: yes, 2017
In this article, we have discovered a connection between the new fractional time derivative of Caputo-Fabrizio and his associated ordinary derivative.
Vincenzo Ciancio
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Fuzzy fractional integral equations under compactness type condition

open access: yes, 2012
In this paper we study a fuzzy fractional integral equation. The fractional derivative is considered in the sense of Riemann-Liouville and we establish existence of the solutions of fuzzy fractional integral equations using the Hausdorff measure of ...
Arshad, Sadia   +3 more
core   +1 more source

Fractional Curvatures of Equiaffine Curves in Three-Dimensional Affine Space

open access: yesJournal of New Theory
This paper presents a method for computing the curvatures of equiaffine curves in three-dimensional affine space by utilizing local fractional derivatives.
Meltem Öğrenmiş
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Numerical simulations for fractional differential equations of higher order and a wright-type transformation

open access: yesPartial Differential Equations in Applied Mathematics
In this work, a new relationship is established between the solutions of higher order fractional differential equations and a Wright-type transformation. Solutions could be interpreted as expected values of functions in a random time process.
M. Nacianceno   +7 more
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Fractional location problems [PDF]

open access: yes
In this paper we analyze some variants of the classical uncapacitated facility location problem with a ratio as an objective function. Using basic concepts and results of fractional programming, we identify a class of one-level fractional location ...
Frenk, J.B.G.   +2 more
core  

Home - About - Disclaimer - Privacy