Results 101 to 110 of about 12,897,520 (259)
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Technical note on a new definition of fractional derivative
In this article, we have discovered a connection between the new fractional time derivative of Caputo-Fabrizio and his associated ordinary derivative.
Vincenzo Ciancio
core
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Fuzzy fractional integral equations under compactness type condition
In this paper we study a fuzzy fractional integral equation. The fractional derivative is considered in the sense of Riemann-Liouville and we establish existence of the solutions of fuzzy fractional integral equations using the Hausdorff measure of ...
Arshad, Sadia +3 more
core +1 more source
Fractional Curvatures of Equiaffine Curves in Three-Dimensional Affine Space
This paper presents a method for computing the curvatures of equiaffine curves in three-dimensional affine space by utilizing local fractional derivatives.
Meltem Öğrenmiş
doaj +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
In this work, a new relationship is established between the solutions of higher order fractional differential equations and a Wright-type transformation. Solutions could be interpreted as expected values of functions in a random time process.
M. Nacianceno +7 more
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Fractional location problems [PDF]
In this paper we analyze some variants of the classical uncapacitated facility location problem with a ratio as an objective function. Using basic concepts and results of fractional programming, we identify a class of one-level fractional location ...
Frenk, J.B.G. +2 more
core

