Results 81 to 90 of about 7,663,513 (304)
Archaeology of Ancient Israelite Religion(s): An Introduction
Israelite religion has always fascinated scholars [...]
Avraham Faust
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We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Nigeria’s democracy: the trilemma of herdsmenism, terrorism and vampirism
Since the ‘invention’ of democracy by the Greek City States in the first half of the 5th Century B.C. and its popularisation after the American War of Independence in the 17th century, democracy has remained the most famous form of government.
Emmanuel O. Ojo
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Men with intellectual disabilities with a history of sexual offending: empathy for victims of sexual and non-sexual crimes [PDF]
Background: The objectives were (a) to compare the general empathy abilities of men with intellectual disabilities (IDs) who had a history of sexual offending to men with IDs who had no known history of illegal behaviour, and (b) to determine whether men
Baron-Cohen +82 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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STIMULUS GENERALIZATION OF BEHAVIORAL HISTORY [PDF]
Undergraduates responded under a variable‐ratio 30 schedule in the presence of a 25‐mm long line and on a differential‐reinforcement‐of‐low‐rate 6‐s schedule when a 13‐mm long line was present. Following this, a line‐length continuum generalization test was administered under a fixed‐interval 6‐s schedule (Experiment 1) or extinction (Experiment 2). In
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
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Oregon Relishes Burgundian Influence [PDF]
Rusty Gaffney gives a year-by-year look at Oregon vintages and a general overview of Willamette Valley wine history in this article from his Prince of Pinot blog, volume 6, issue 36.
Gaffney, William Rusty
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