Results 41 to 50 of about 11,466,083 (284)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The Mellin Transform of Logarithmic and Rational Quotient Function in terms of the Lerch Function
Journal of Mathematics, 2021 Upon reading the famous book on integral transforms volume II by Erdeyli et al., we encounter a formula which we use to derive a Mellin transform given by ∫0∞xm−1logkax/β2+x2γ+xdx, where the parameters a,k,β, and γ are general complex numbers.
Robert Reynolds, Allan Stauffer
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Mehler-Fock transform of general order and arbitrary index and its inversion
International Journal of Mathematics and Mathematical Sciences, 1984 An integral transform involving the associated Legendre function of zero order, P−12+iτ(x), x∈[1,∞), as the kernel (considered as a function of τ), is called Mehler-Fock transform. Some generalizations, involving the function P−12+iτμ(x), where the order
Cyril Nasim
doaj +1 more source
Generalized Fractional Integration of the H-Function Involving General Class of Polynomials
Walailak Journal of Science and Technology, 2014 In the present paper, we consider 2 integral transforms involving the Appell function F3 in the kernels. They generalize the fractional integral operators given by Saigo (1978).
Dinesh KUMAR +2 more
doaj +1 more source
On the general transformation of the Wirtinger integral
Hokkaido University Preprint Series in Mathematics, 2008 For the theta functions \(\theta_{00}(\nu,\tau)\), \(\theta_{01}(\nu,\tau)\), \(\theta_{10}(\nu,\tau)\), \(\theta_{11}(\nu,\tau)\), the author considers two functions \(z_1(\tau)\) and \(z_2(\tau)\), called Wirtinger integrals, and discusses the problem to find the coefficients \(A\) and \(B\) with respect to \(\tau\) such that \(z_1\left(\frac{a\tau+b}
openaire +5 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source