Results 31 to 40 of about 1,179,697 (255)

Robustness Property of Robust-BD Wald-Type Test for Varying-Dimensional General Linear Models

Entropy, 2018
An important issue for robust inference is to examine the stability of the asymptotic level and power of the test statistic in the presence of contaminated data.
Xiao Guo, Chunming Zhang
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Sparsifying Generalized Linear Models

Proceedings of the 56th Annual ACM Symposium on Theory of Computing
We consider the sparsification of sums $F : \mathbb{R}^n \to \mathbb{R}$ where $F(x) = f_1(\langle a_1,x\rangle) + \cdots + f_m(\langle a_m,x\rangle)$ for vectors $a_1,\ldots,a_m \in \mathbb{R}^n$ and functions $f_1,\ldots,f_m : \mathbb{R} \to \mathbb{R}_+$.
Arun Jambulapati, James R. Lee, Yang P. Liu, Aaron Sidford   +3 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Generalized linear models

, 2015
AbstractGeneralized Linear Modeling (GLM) unifies several statistical techniques, providing a stable and modular foundation on which to build a useful working knowledge of statistical modeling. GLMs enable a re-interpretation of previously learned ANOVA and regression techniques and integrate well with more advanced modeling techniques introduced in ...
  +6 more sources

Longitudinal surface‐based spatial Bayesian GLM reveals complex trajectories of motor neurodegeneration in ALS

NeuroImage, 2022
Longitudinal fMRI studies hold great promise for the study of neurodegenerative diseases, development and aging, but realizing their full potential depends on extracting accurate fMRI-based measures of brain function and organization in individual ...
Amanda F. Mejia, Vincent Koppelmans, Laura Jelsone-Swain, Sanjay Kalra, Robert C. Welsh   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A Parametric Model for Local Air Exchange Rate of Naturally Ventilated Barns

Agronomy, 2021
With an increasing number of naturally ventilated dairy barns (NVDBs), the emission of ammonia and greenhouse gases into the surrounding environment is expected to increase as well.
E. Moustapha Doumbia, David Janke, Qianying Yi, Alexander Prinz, Thomas Amon, Martin Kriegel, Sabrina Hempel   +6 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source