Results 271 to 280 of about 8,779,065 (357)

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

A mixed methods process evaluation of a collaborative outpatient palliative care clinic for patients with end-stage liver disease. [PDF]

BMC Palliat Care
Warmels G, Wills A, Bruni A, Cohen L, Kelly E, Downar J, Patel AA, Dargavel G, Rauthu S, Isenberg SR.   +9 more
europepmc   +1 more source

Rapid Arbitrary‐Shape Microscopy of Unsectioned Tissues for Precise Intraoperative Tumor Margin Assessment

Advanced Science, EarlyView.
This study presents a novel microscopic imaging system capable of rapid, section‐free scanning of irregular tissue surfaces, delivering high sensitivity for detecting cancer cell clusters during intraoperative tumor margin assessment. Abstract Rapid and accurate intraoperative examination of tumor margins is crucial for precise surgical treatment, yet ...
Zhicheng Shao, Xiangwei Meng, Peifen Fu, Keer Huang, Xibei Chen, Yue Ying, Jun Li, Yuxin Zheng, Xiaolong Li, Hyeon Jeong Lee, Jingyi Feng, Yuexin Lu, Runping Cai, Xiongling Jiang, Qing Chen, Hong Zhang, Xiaoyong Man, Li Lin   +17 more
wiley   +1 more source

Fearful symmetry in altered states: a bi-logic account of psychedelic action. [PDF]

Front Psychol
Goldreich M.
europepmc   +1 more source

Unpaired Learning‐Enabled Nanotube Identification from AFM Images

Advanced Science, EarlyView.
Identifying nanotubes on rough substrates is notoriously challenging for conventional image analysis. This work presents an unpaired deep learning approach that automatically extracts nanotube networks from atomic force microscopy images, even on complex polymeric surfaces used in roll‐to‐roll printing.
Soyoung Na, Soobin Park, Younsu Jung, Jinhwa Park, Jimin Hong, Jihyun Lee, Albert Kim, Bongjun Kim, Gyoujin Cho, Eunju Cha, Seung Hyun Song   +10 more
wiley   +1 more source

Analyzing EEG data during opium addiction treatment using a fuzzy logic-based machine learning model. [PDF]

Front Psychiatry
DehAbadi E, Anka FA, Vafaei F, Lanjanian H, Nematzadeh S, Torkamanian-Afshar M, Aghahosseinzargar N, Kiani F, Hassani-Abharian P.   +8 more
europepmc   +1 more source

Teaching Competencies of Senior High School Teachers Relative to the Content Standards on Logic in General Mathematics

N.L. Mitra
openalex   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization. [PDF]

Biol Open
Ahmadi M, Rudolf H, Mau C, Garcia-Guillen J, El-Sherif E.   +4 more
europepmc   +1 more source