Results 131 to 140 of about 3,954,320 (257)

Bridging Dementia Care in Japan: The Emerging Role of General Medicine Physicians. [PDF]

J Clin Med
Yamasaki T.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Barriers and Associated Factors to Writing Case Reports Among Japanese General Medicine Physicians: A Cross-Sectional Study of the Japan Primary Care Association Members. [PDF]

J Gen Fam Med
Kenzaka T, Yahata S, Mizutani N, Kumabe A, Fujiwara R, Kyotani M, Kosami K, Mori H.   +7 more
europepmc   +1 more source

General Internal Medicine

Journal of the Royal College of Physicians of London, 1986
R C, King, C, Davidson
openaire   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Cluster-Randomized Controlled Trial of Enhanced Carbapenem-Resistant Enterobacterales Prevention Program in General Medicine Wards, Siriraj Hospital. [PDF]

Clin Infect Dis
Taweesuk A, Rattanaumpawan P, Rachakhom S, Wangchinda W, Assanasen S, Thamlikitkul V.   +5 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Trends and Challenges in Orthopedic Referrals Following the Development of a General Medicine Department in a Community Hospital: A Mixed-Methods Study. [PDF]

Cureus
Nishikawa K, Ohta R, Sano C.
europepmc   +1 more source

Geriatric Medicine and General Internal Medicine

Journal of the Royal College of Physicians of London, 1984
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source