Results 111 to 120 of about 4,061,047 (303)

General internal medicine and family medicine journals

open access: yes, 2020
Like research in general internal medicine, family medicine research can play an important role in improving medical knowledge. We aimed to compare articles published in family medicine journals with articles published in general internal medicine ...
Paul Sebo, Seboe, Paul
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Determination of highly linked free e-journals for Medicine courses in Jondi Shapour Ahvaz University (Iran)

open access: yes, 2006
Now, there are many free electronic journals accessible for their readers on the Web. Many of the academic staff and students, especially in developing countries are using these journals to fulfill their academic needs. However, not all of these journals
Asnafi, Amir Reza
core  

Standardization Guidelines for Chinese Medicine Rehabilitation

open access: yes, 2019
To further facilitate the public health project"Standardization of Capacity Construction of TCM Rehabilitation Service", Chinese Medicine of Technology and Development Center for TCM of China and Research Base of Standards of Chinese Medicine ...
Weichi GUO   +6 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

The Characteristics of General Medicine Thesis in Kermanshah University of Medical Sciences during Five Years Periods

open access: yesآموزش پزشکی, 2018
BACKGROUND AND OBJECTIVE: Doing and writing the qualified thesis could be considered as the onset of the research proceeding and formation of academic identity of students.
Mohammad rasoul Khazaee   +3 more
doaj  

Functional neurological disorder mimicking stroke: A case report

open access: yesClinical Case Reports
KEY CLINICAL MESSAGE Even in the era of technology‐guided medicine, the clinician must integrate into his daily practice a careful anamnesis and physical examination to be conducted within a close doctor–patient relationship. All these elements, together
G. Venturini, C. Sarti
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Evidence-based medicine and general practice.

open access: yes, 1997
Evidence-based medicine (EBM) aids clinical decision making in all fields of medicine, including primary care. General practice is characterized by particular emphasis on the doctor-patient relationship and on biomedical, personal and contextual ...
Butler, Christopher Collett   +7 more
core  

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