Results 141 to 150 of about 3,411,735 (299)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

The Consumption of Alcohol and of Other Medicines at the Massachusetts General Hospital [PDF]

, 1909
Richard C. Cabot
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Treatment in General Medicine

, 1939
Hobart A. Reimann
openalex   +2 more sources

GENERAL IDEAS IN MEDICINE [PDF]

BMJ, 1935
openaire   +3 more sources

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Oser l’incertain. L’imputation des effets indésirables médicamenteux.

Anthropologie & Santé
How do doctors impute adverse drug reactions (ADRs)? This operation, neither obvious nor natural, involves relevant health issues, particularly the report to the Adverse Drug Reporting System.
Anne-Chantal Hardy
doaj   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source

The Opinions of Graduated Students of Medicine on the Amount of Compatibility Existing between the Programs of Clinical Education and their Occupation Needs in Kerman

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2010
BACKGROUND AND OBJECTIVE: The significance of the occupation of medical doctors has given great importance to the methods used in medical education of training.
Z Ghazanfari,, M Forozy, F Khosravi
doaj  

Evaluation of Arginase Activity in Normal Epidermal Tissue and Pathological Stratum Corneum11From the Dermatology Service, General Medicine Branch, National Cancer Institute, National Institutes of Health, Public Health Service, U.S. Department of Health, Education, and Welfare, Bethesda, Maryland.

, 1958
Simon Rothberg, Eugene J. Van Scott, S.L. Newberry   +2 more
openalex   +1 more source