Results 151 to 160 of about 9,526,118 (278)
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
THE AMERICAN YEAR-BOOK OF MEDICINE AND SURGERY, being a Yearly Digest of Scientific Progress and Authoritative Opinion in all Branches of Medicine and Surgery, under the general editorial charge of GEORGE M. GOULD, M.D. SURGERY. Philadelphia and London [PDF]
, 1902 Charles H. Goodrich
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
THE RELATION OF GENERAL MEDICINE TO OPHTHALMOLOGY. [PDF]
, 1920 Charles Higgens
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Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Throat and nose affections and their relation to general medicine [PDF]
, 1898 Walter F. Chappell
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
ADDRESS ON GENERAL MEDICINE. THE MALARIAL DISORDERS OF LARGE CITIES, WITH ESPECIAL REFERENCE TO CHICAGO. [PDF]
, 1895 WM. E. QUINE
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Intelligent Understanding of Large Language Models in Traditional Chinese Medicine Based on Prompt Engineering Framework [PDF]
arXivThis paper explores the application of prompt engineering to enhance the performance of large language models (LLMs) in the domain of Traditional Chinese Medicine (TCM). We propose TCM-Prompt, a framework that integrates various pre-trained language models (PLMs), templates, tokenization, and verbalization methods, allowing researchers to easily ...
arxiv