Results 71 to 80 of about 14,270,971 (389)
Ophthalmology and general medicine [PDF]
This ophthalmological perspective of general medicine attempts to deal with the more common situations encountered clinically in general ophthalmic practice. Some priority has been given to the clinical usefulness of data. A comprehensive review would involve a wide range of rare conditions and has not been attempted.
openaire +2 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Key Clinical Message While intermittent hemodialysis (HD) is the most efficient method of removing lithium in patients with lithium toxicity, continuous renal replacement therapy is an acceptable alternative in the setting of intradialytic hypotension ...
Pooya Zardoost+6 more
doaj +1 more source
"It isn't just consultants that need a BSc": student experiences of an Intercalated BSc [PDF]
More medical schools are moving towards a compulsory intercalated BSc. These courses have not traditionally been aimed at those students interested in general practice and have tended to have limited clinical relevance.
Jones, M., Lloyd, M., Singh, S.
core
High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E.+12 more
core +1 more source
BackgroundSufficiently detailed abstracts of randomized controlled trials (RCTs) are important, because readers often base their assessment of a trial solely on information in the abstract.
J. Bigna+6 more
semanticscholar +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász+6 more
wiley +1 more source
Takashi Watari,1– 3 Yasuhisa Nakano,4 Ashwin Gupta,2,3 Minami Kakehi,4 Ayuko Tokonami,4 Yasuharu Tokuda5 1General Medicine Center, Shimane University Hospital, Izumo, Shimane, Japan; 2Department of Medicine, University of Michigan Medical School, Ann ...
Watari T+5 more
doaj
Evaluating the Current Status of Education in Family Physicians in Iranian Medical Schools [PDF]
Introduction: Family physicians in Iran suffer from lack of relevant knowledge, competencies, and skills. Improving the training program requires examining the currently provided education in the field of Family Physician.
A Heidarzadeh+5 more
doaj
Objective Although several studies have been conducted worldwide on factors that might improve residents' knowledge, the relationship between the hospital volume and the internal medicine residents' knowledge has not been fully understood. We conducted a
A. Mizuno+8 more
semanticscholar +1 more source