Results 101 to 110 of about 2,849,424 (255)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

General Mental Health Status Scores of Patients with Atypical Chest Pain, a Case-Control Study

Bihdād, 2019
Objectives: Psychological problems could have some relationship with undetermined chest pain. The aim of this study was to compare the general mental health status of out-patients with atypical chest pain with a reference age and sex matched controls ...
Mehdi Mousavi, Seyed Abbas Mousavi, Mustafa Raeisi, Delara Salehifar   +3 more
doaj  

Survey on Nondeterministic Optimal Design and Its Applications in the Aerospace Industry [PDF]

فصلنامه علوم و فناوری فضایی, 2012
The purpose of this paper is introducing the concept of nondeterministic optimal design or optimal design in the presence of uncertainty based on researches done in the past two decades. Therefore, after an introduction about uncertainty, the uncertainty
J. Roshanian, M. Ebrahimi, A. Bataleblu
doaj  

Appropriate standards of physical fitness of students

Слобожанський науково-спортивний вісник, 2016
Purpose: to establish the due norms and estimates of the level of development of physical fitness of students. Material & Methods: the assessment of physical fitness of students (young men) was carried out on the basis of the results, which are shown by ...
Larisa Lutsenko, Vjаcheslav Shuteev, Anastasija Sutula, Olga Sutula, Alfiya Deyneko   +4 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Gender-Specific Differences in Low-Dose Haloperidol Response for Prevention of Postoperative Nausea and Vomiting: A Register-Based Cohort Study.

PLoS ONE, 2016
BackgroundPostoperative nausea and vomiting (PONV) is one of the most common and distressing complications after general anesthesia and surgery, with young non-smoking females receiving postoperative opioids being high-risk patients.
Florian Brettner, Silke Janitza, Kathrin Prüll, Ernst Weninger, Ulrich Mansmann, Helmut Küchenhoff, Alexander Jovanovic, Bernhard Pollwein, Daniel Chappell, Bernhard Zwissler, Vera von Dossow   +10 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study

Journal of Cardiovascular Magnetic Resonance, 2018
Background Although endothelial cell adhesion molecules (CAMs) are postulated to play a key role in early atherosclerosis, studies on endothelial CAMs are mainly pertained to middle-aged populations and populations with an unfavourable cardiovascular ...
Anouk L. M. Eikendal, Michiel L. Bots, Aisha Gohar, Esther Lutgens, Imo E. Hoefer, Hester M. den Ruijter, Tim Leiner   +6 more
doaj   +1 more source

Technical support for creating an artificial intelligence system for feature extraction and experimental design [PDF]

Techniques for classifying objects into groups or clases go under many different names including, most commonly, cluster analysis. Mathematically, the general problem is to find a best mapping of objects into an index set consisting of class identifiers.
Glick, B. J.
core   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source