Results 41 to 50 of about 122,842,211 (270)

TRANSPORT OF PATIENTS FOR PRIMARY PTCA FROM GENERAL HOSPITAL NOVO MESTO TO LJUBLJANA IN 2002

open access: yesZdravniški Vestnik, 2004
Background. The treatment of acute coronary syndrome (ACS) with ST-segment elevation with primary percutaneous transluminal coronary angioplasty (PTCA) is the best way to treat these patients.
Renata Okrajšek, Rafael Kapš
doaj  

Alcohol consumption, arterial blood pressure and general mortality rate: Twenty-years follow-up study [PDF]

open access: yesVojnosanitetski Pregled, 2004
Background. Alcohol consumption has both adverse and beneficial effects on health and survival. The aim of this prospective study was to examine the association between alcohol consumption and arterial hypertension as well as general mortality rate ...
Jakovljević Branko   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Adenoma detection rates during screening colonoscopy performed by interventional gastroenterologists and general gastroenterologists

open access: yesiGIE
Background and Aims: Interventional gastroenterologists typically perform colonoscopies at lower volumes than general gastroenterologists, and we sought to determine whether this disparity affects their overall adenoma detection rates (ADRs).
Jordan Burlen, MD   +11 more
doaj   +1 more source

Cognitive–behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis

open access: yesHealth Technology Assessment, 2021
Background: Cognitive–behavioural therapy aims to increase quality of life by changing cognitive and behavioural factors that maintain problematic symptoms.
Beth Fordham   +15 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Inferences for the GKME Distribution Under Progressive Type-I Interval Censoring with Random Removals and Its Application to Survival Data

open access: yesAxioms
The analysis of lifetime data under censoring schemes plays a vital role in reliability studies and survival analysis, where complete information is often difficult to obtain. This work focuses on the estimation of the parameters of the recently proposed
Ela Verma   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Effects of Neostigmine and Sugammadex for Reversal of Neuromuscular Blockade on QT Dispersion Under Propofol Anesthesia: A Randomized Controlled Trial

open access: yesCardiology and Therapy, 2018
Introduction Reversal of non-depolarizing neuromuscular blocking agent neostigmine is associated with QT prolongation under general anesthesia. To clarify the effects of neostigmine and sugammadex on hemodynamic status, the QT interval and QT dispersion ...
Yusuke Yamashita   +4 more
doaj   +1 more source

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