Results 151 to 160 of about 116,475 (314)

Linear versus nonlinear causalityfor dax companies [PDF]

open access: yes
This study provides empirical evidence of the joint dynamics between stock returns and trading volume using stock data for DAX companies. Our research confirms the hypothesis that traditional linear causality tests often fail to detect some kinds of ...
Henfryk Gurgul, lukasz Lach
core  

Dual Physiological Barriers Bypassed by a Silk‐Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu   +5 more
wiley   +1 more source

Estimation and model specification testing in nonparametric and semiparametric econometric models

open access: yes
This paper considers two classes of semiparametric nonlinear regression models, in which nonlinear components are introduced to reflect the nonlinear fluctuation in the mean.
King, Maxwell, Gao, Jiti
core  

General Framework for Nonlinear Functional Regression with Reproducing Kernel Hilbert Spaces

open access: yes, 2009
In this paper, we discuss concepts and methods of nonlinear regression for functional data. The focus is on the case where covariates and responses are functions. We present a general framework for modelling functional regression problem in the Reproducing Kernel Hilbert Space (RKHS).
Kadri, Hachem   +4 more
openaire   +1 more source

Generalized nonlinear percentile regression using asymmetric maximum likelihood estimation

open access: yesCommunications for Statistical Applications and Methods, 2021
Juhee Lee, Young Min Kim
openaire   +2 more sources

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

open access: yesAdvanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng   +12 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Testing for lack of fit in inverse regression - with applications to photonic imaging. [PDF]

open access: yes
Regression; Problems; Lack-of-fit; Applications;
Claeskens, Gerda   +3 more
core  

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

open access: yesAdvanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang   +2 more
wiley   +1 more source

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