Results 11 to 20 of about 1,535 (117)

Comparison of the World Pharmacopoeias’ Requirements for the Quality of Cell Lines

Биопрепараты: Профилактика, диагностика, лечение, 2020
The cell line is one of the necessary components of a biomedical cell product (BMCP) which can include only viable human cells. In addition, human, animal, insect, or bacterial cell lines can be used as a substrate for the production of some biological ...
M. A. Vodyakova, A. R. Sayfutdinova, E. V. Melnikova, Yu. V. Olefir   +3 more
doaj   +1 more source

Variability of total flavonoid and mucilage content of wild growing chamomile (Matricaria recutita L.) populations

Julius-Kühn-Archiv, 2016
During our investigation 50 wild growing chamomile populations’ active substance content, among them total flavonoid content and swelling index referring to mucilage content were examined in 2009 in the main chamomile collection areas of Hungary ...
Gosztola, Beáta , Németh-Zámbori, Éva   +1 more
doaj   +1 more source

Development and Validation of Sibutramine Determination in Drug Products by Capillary Electrophoresis

Разработка и регистрация лекарственных средств, 2020
Introduction. Recently, there has been a growing trend in the number of obese and overweight patients. To date, sibutramine is the most effective drug for treating obesity and overweight.
A. M. Sukhanova, I. B. Perova, K. I. Eller, G. M. Rodionova, S. V. Chernova, V. N. Kuzina   +5 more
doaj   +1 more source

Standardisation of human immunoglobulin preparations: Harmonising Russian State pharmacopoeia with world quality standards

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Human immunoglobulin preparations (HIP) used in medicine effectively treat autoimmune diseases, inflammatory diseases, and immune deficiencies and prevent diseases of various aetiologies.
O. A. Demidova, O. G. Kornilova, V. L. Bagirova   +2 more
doaj   +1 more source

The sodium 5-butyl-1,2-diphenyl-6-oxo-1,6-dihydropyrimidine-4-olate quantitative content determination in a standard sample

Разработка и регистрация лекарственных средств, 2021
Introduction. The standard samples (SS) use is a necessary condition for the medicines' quality control implementation. Their development is an urgent problem for the pharmaceutical industry, especially for new biologically active compounds that can be ...
E. V. Kuvaeva, D. A. Kolesnik, P. O. Levshukova, I. I. Terninko, I. P. Yakovlev, E. V. Fedorova   +5 more
doaj   +1 more source

Validation Testing of Sabouraud Liquid Medium in Determining the Antifungal Activity of Newly Synthesized compounds by the Method of Two-fold Serial Dilutions

Разработка и регистрация лекарственных средств, 2022
Introduction. Due to the high prevalence and social significance of fungal infections, the search for new antifungal drugs is an actual direction t of modern pharmacology.
V. V. Novikova, N. A. Pulina, V. G. Luzhanin, E. R. Kurbatov   +3 more
doaj   +1 more source

Approaches to Assessing the Quality of Fatty Oils and Medicinal Products Formulated as Oily Solutions

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Vegetable fatty oils can comprise over 50% of a medicinal product formulated as an oily solution (in some cases, 100%). The quality of the vegetable fatty oil used and the processes occurring in this oil have a significant impact on the ...
A. A. Ponomarenko, L. I. Panova
doaj   +1 more source

Development and Validation of a Procedure for the Quantitative Determination of Residual Organic Solvents in Allergen Preparations by GC

Разработка и регистрация лекарственных средств, 2022
Introduction. One of the requirements for the quality of pharmaceuticals, including allergens, is the determination of residual organic solvents in them.
R. A. Bubenchikov, E. I. Sakanyan, N. V. Zubkova, V. P. Dobrynin, S. V. Goriainov, F. Hajjar, E. A. Platonov, D. I. Pisarev, R. A. Abramovich   +8 more
doaj   +1 more source

Isatis tinctoria L. (Woad): A Review of Its Botany, Ethnobotanical Uses, Phytochemistry, Biological Activities, and Biotechnological Studies

Plants, 2020
Isatis tinctoria L. (Brassicaceae), which is commonly known as woad, is a species with an ancient and well-documented history as an indigo dye and medicinal plant. Currently, I.
Jasmine Speranza, Natalizia Miceli, Maria Fernanda Taviano, Salvatore Ragusa, Inga Kwiecień, Agnieszka Szopa, Halina Ekiert   +6 more
doaj   +1 more source

Standardisation of the method for prekallikrein activator determination in human immunoglobulin and albumin products

Биопрепараты: Профилактика, диагностика, лечение, 2022
Assessment of prekallikrein content is essential for safety control of human immunoglobulin and albumin products. The inherent variability of human prekallikrein reagents and chromogenic substrates indicates the need for standardisation of the ...
O. G. Kornilova, M. A. Krivykh, A. A. Voropaev, O. V. Fadeikina, R. A. Volkova   +4 more
doaj   +1 more source