Results 21 to 30 of about 1,606 (135)

Approaches to Assessing the Quality of Fatty Oils and Medicinal Products Formulated as Oily Solutions

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Vegetable fatty oils can comprise over 50% of a medicinal product formulated as an oily solution (in some cases, 100%). The quality of the vegetable fatty oil used and the processes occurring in this oil have a significant impact on the ...
A. A. Ponomarenko, L. I. Panova
doaj   +1 more source

Conservation status of species used in the UK herbal medicine industry

PLANTS, PEOPLE, PLANET, EarlyView.
Given the ongoing biodiversity crisis, sustainable use and management of medicinal plants is critical. We assessed the conservation status, threats and conservation actions of 298 species sold by UK suppliers to medical herbalists. We found that most species used are unevaluated, representing a gap in conservation knowledge, and of those with ...
Isabella Flowers, Jon C. Lovett, Christopher Hassall   +2 more
wiley   +1 more source

Development and Validation of a Procedure for the Quantitative Determination of Residual Organic Solvents in Allergen Preparations by GC

Разработка и регистрация лекарственных средств, 2022
Introduction. One of the requirements for the quality of pharmaceuticals, including allergens, is the determination of residual organic solvents in them.
R. A. Bubenchikov, E. I. Sakanyan, N. V. Zubkova, V. P. Dobrynin, S. V. Goriainov, F. Hajjar, E. A. Platonov, D. I. Pisarev, R. A. Abramovich   +8 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1287-1308, May 2026.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Isatis tinctoria L. (Woad): A Review of Its Botany, Ethnobotanical Uses, Phytochemistry, Biological Activities, and Biotechnological Studies

Plants, 2020
Isatis tinctoria L. (Brassicaceae), which is commonly known as woad, is a species with an ancient and well-documented history as an indigo dye and medicinal plant. Currently, I.
Jasmine Speranza, Natalizia Miceli, Maria Fernanda Taviano, Salvatore Ragusa, Inga Kwiecień, Agnieszka Szopa, Halina Ekiert   +6 more
doaj   +1 more source

Replacing Ecologically Risky Trifluoroacetic Acid and Acetonitrile With Methanesulfonic Acid and Dimethyl Carbonate in High‐Performance Liquid Chromatography Analyses of Small Molecule Drugs

Journal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT It has long been recognised that, in the long term, hazardous acetonitrile (ACN) as a mobile‐phase component and the environmentally critical trifluoroacetic acid (TFA) as an ion‐pairing reagent should be replaced in high‐performance liquid chromatography (HPLC).
Franziska Pögel neé Steinicke, Taha B. El‐Jourani, Jana Haegner, Matthias Schiedel, Hermann Wätzig   +4 more
wiley   +1 more source

A Network Pharmacology and Experimental Validation Strategy for Hypoglycemic Study of Lonicerae Japonicae Flos on Diabetes

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT As diabetes has become an important public health issue, Lonicerae Japonicae Flos (LJF) had gradually attracted increasing attention on diabetes. This study aimed to investigate the hypoglycemic ingredients and underlying mechanisms of LJF in diabetes using an integrated strategy of network pharmacology, molecular docking and experimental ...
Zhang Nan, Liu Xiaolong, Li Chunyan, Ren Lu, Guo Chao, Xue Jintao   +5 more
wiley   +1 more source

Sampling in modern pharmaceutical analysis

Регуляторные исследования и экспертиза лекарственных средств, 2018
Sampling procedure is an integral part of the drug quality control system. Objective science-based sampling is an important operation when only a small amount of a material is taken and it is representative for the analysis of the whole product batch ...
T. N. Bokovikova, E. P. Gernikova, E. I. Sakanyan, N. D. Bunyatyan, L. I. Shishova, L. A. Stronova, S. A. Manaeva   +6 more
doaj  

Standardisation of the method for prekallikrein activator determination in human immunoglobulin and albumin products

Биопрепараты: Профилактика, диагностика, лечение, 2022
Assessment of prekallikrein content is essential for safety control of human immunoglobulin and albumin products. The inherent variability of human prekallikrein reagents and chromogenic substrates indicates the need for standardisation of the ...
O. G. Kornilova, M. A. Krivykh, A. A. Voropaev, O. V. Fadeikina, R. A. Volkova   +4 more
doaj   +1 more source