Results 11 to 20 of about 1,606 (135)

Comparative analysis of quality attributes of a human albumin preparation with a modified stabilising composition

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. The national and international human albumin preparations registered in the Russian Federation mainly differ in their excipient compositions.
M. V. Tomilin, T. V. Korotkova, P. A. Loginov   +2 more
doaj   +1 more source

Introducing a Novel Biorelevant In Vitro Dissolution Method for the Assessment of Nicotine Release from Oral Tobacco-Derived Nicotine (OTDN) and Snus Products

Separations, 2022
The rate at which oral tobacco-derived nicotine (OTDN) and snus pouches release nicotine into saliva is crucial to determine product performance.
Matthias M. Knopp, Nikolai K. Kiil-Nielsen, Anna E. Masser, Mikael Staaf   +3 more
doaj   +1 more source

The possibility of harmonizing the recombinant erythropoietin specific activity determination method with European Pharmacopoeia

Стандартные образцы, 2017
Rationale. The task of import substitution in health care and the development of normative legal acts in the framework of the Eurasian Economic Community raises the questions of harmonization of national requirements with international ones, including ...
A. K. Yakovlev, L. A. Gayderova, V. N. Podkuiko, R. A. Volkova, N. A. Alpatova, Yu. V. Olefir   +5 more
doaj   +1 more source

xperimental Evaluation of the Possibility of using the LAL test to Determine Bacterial Endotoxins in Vaccines for Rabies Prophylaxis

Эпидемиология и вакцинопрофилактика, 2021
Relevance. The presence of pyrogenic impurities in finished dosage forms of concentrated cultural anti-rabies vaccines produced in the Russian Federation is determined using pyrogenicity tests on rabbits (in vivo).
A. V. Muhacheva, O. A. Barkhaleva, O. V. Shapovalova, N. P. Neugodova, A. Yu. Butirskiy, A. A. Movsesyants, R. A. Volkova, K. A. Sarkisyan   +7 more
doaj   +1 more source

Comparison of the World Pharmacopoeias’ Requirements for the Quality of Cell Lines

Биопрепараты: Профилактика, диагностика, лечение, 2020
The cell line is one of the necessary components of a biomedical cell product (BMCP) which can include only viable human cells. In addition, human, animal, insect, or bacterial cell lines can be used as a substrate for the production of some biological ...
M. A. Vodyakova, A. R. Sayfutdinova, E. V. Melnikova, Yu. V. Olefir   +3 more
doaj   +1 more source

Variability of total flavonoid and mucilage content of wild growing chamomile (Matricaria recutita L.) populations

Julius-Kühn-Archiv, 2016
During our investigation 50 wild growing chamomile populations’ active substance content, among them total flavonoid content and swelling index referring to mucilage content were examined in 2009 in the main chamomile collection areas of Hungary ...
Gosztola, Beáta , Németh-Zámbori, Éva   +1 more
doaj   +1 more source

Standardisation of human immunoglobulin preparations: Harmonising Russian State pharmacopoeia with world quality standards

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Human immunoglobulin preparations (HIP) used in medicine effectively treat autoimmune diseases, inflammatory diseases, and immune deficiencies and prevent diseases of various aetiologies.
O. A. Demidova, O. G. Kornilova, V. L. Bagirova   +2 more
doaj   +1 more source

Development and Validation of Sibutramine Determination in Drug Products by Capillary Electrophoresis

Разработка и регистрация лекарственных средств, 2020
Introduction. Recently, there has been a growing trend in the number of obese and overweight patients. To date, sibutramine is the most effective drug for treating obesity and overweight.
A. M. Sukhanova, I. B. Perova, K. I. Eller, G. M. Rodionova, S. V. Chernova, V. N. Kuzina   +5 more
doaj   +1 more source

The sodium 5-butyl-1,2-diphenyl-6-oxo-1,6-dihydropyrimidine-4-olate quantitative content determination in a standard sample

Разработка и регистрация лекарственных средств, 2021
Introduction. The standard samples (SS) use is a necessary condition for the medicines' quality control implementation. Their development is an urgent problem for the pharmaceutical industry, especially for new biologically active compounds that can be ...
E. V. Kuvaeva, D. A. Kolesnik, P. O. Levshukova, I. I. Terninko, I. P. Yakovlev, E. V. Fedorova   +5 more
doaj   +1 more source

Validation Testing of Sabouraud Liquid Medium in Determining the Antifungal Activity of Newly Synthesized compounds by the Method of Two-fold Serial Dilutions

Разработка и регистрация лекарственных средств, 2022
Introduction. Due to the high prevalence and social significance of fungal infections, the search for new antifungal drugs is an actual direction t of modern pharmacology.
V. V. Novikova, N. A. Pulina, V. G. Luzhanin, E. R. Kurbatov   +3 more
doaj   +1 more source