Results 51 to 60 of about 2,657,945 (266)
Exchanging Best Practices and Tools for Supporting Computational and Data-Intensive Research, The Xpert Network [PDF]
arXiv, 2021 We present best practices and tools for professionals who support computational and data intensive (CDI) research projects. The practices resulted from an initiative that brings together national projects and university teams that include individual or groups of such professionals.
arxiv
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
FEBS Letters, EarlyView.The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine +3 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Gastroenterology Research and Practice, 2023 Aim. In clinical practice, a considerable proportion of patients with chronic hepatitis B (CHB) who do not conform to any immune status are considered to be in the “indeterminate phase”.
Shanshan Chen +5 more
doaj +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
BMC Health Services Research, 2019 Background At the end of life, about 85–90% of patients can be treated within primary palliative care (PC) provided by general practitioners (GPs). In Germany, there is no structured approach for the provision of PC by GPs including a systematic as well ...
Kambiz Afshar +7 more
doaj +1 more source
BMC Medical Education, 2023 Introduction To determine the effectiveness of the Star Family Doctors Training Program, a comprehensive Continuing professional development (CPD) program for general practitioners (GPs) in a compact medical consortium. Patients and Methods Observational
Ling-Bo Liang +7 more
doaj +1 more source
Embodying the Glitch: Perspectives on Generative AI in Dance Practice [PDF]
arXiv, 2022 What role does the break from realism play in the potential for generative artificial intelligence as a creative tool? Through exploration of glitch, we examine the prospective value of these artefacts in creative practice. This paper describes findings from an exploration of AI-generated "mistakes" when using movement produced by a generative deep ...
arxiv
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source