Results 51 to 60 of about 22,988 (314)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Relativistic Spin Precession in the Compact Double Neutron Star System PSR J1946+2052
The Astrophysical JournalWe observe systematic profile changes in the visible pulsar of the compact double neutron star system PSR J1946+2052 using observations with the Five-hundred-meter Aperture Spherical radio Telescope (FAST). The interpulse of PSR J1946+2052 changed from a
Lingqi Meng +18 more
doaj +1 more source
Spherically symmetric elastic bodies in general relativity [PDF]
, 2023 Artur Alho +3 more
openalex +1 more source
Embeddings for general relativity [PDF]
Classical and Quantum Gravity, 2015 Accepted for publication in Classical and Quantum ...
openaire +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
On Conformally Coupled General Relativity
EPJ Web of Conferences, 2018 A gravity model based on the conformal symmetry is presented. To specify the structure of the general coordinate transformations the Ogievetsky theorem is applied. The nonlinear symmetry realization approach is used.
Arbuzov Andrej, Latosh Boris
doaj +1 more source
Testing general relativity on accelerators
Physics Letters B, 2015 Within the general theory of relativity, the curvature of spacetime is related to the energy and momentum of the present matter and radiation. One of the more specific predictions of general relativity is the deflection of light and particle trajectories
Tigran Kalaydzhyan
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
General Relativity today [PDF]
, 2007 49 pages, 5 figures, talk given at the Poincar\'e Seminar ``Gravitation et Exp\'erience'' (28 October 2006, Paris); to appear in the proceedings to be published by Birkh ...
openaire +2 more sources